Left Ventricular Function Assessed by One-Point Carotid Wave Intensity in Newly Diagnosed Untreated Hypertensive Patients

被引:5
作者
Vriz, Olga [1 ]
Favretto, Serena [2 ]
Jaroch, Joanna [3 ]
Wojciech, Rychard [2 ]
Bossone, Eduardo [4 ]
Driussi, Caterina [1 ]
Antonini-Canterin, Francesco [5 ]
Palatini, Paolo [6 ]
Loboz-Grudzien, Krystyna [2 ]
机构
[1] St Antonio Hosp, Dept Cardiol & Emergency Med, Udine, Italy
[2] Univ Piemonte Orientale, Dept Translat Med, Novara, Italy
[3] Wroclaw Med Univ, Dept Cardiol, T Marciniak Hosp, Wroclaw, Poland
[4] Univ Salerno, Heart Dept, Dept Cardiol, Cava de Tirreni & Amalfi Coast Hosp, Salerno, Italy
[5] Santa Maria degli Angeli Hosp, Dept Cardiol, Pordenone, Italy
[6] Univ Padua, Dept Internal Med, Padua, Italy
关键词
echocardiography; hypertension; left ventricular function; wave intensity; DIASTOLIC BLOOD-PRESSURE; END-SYSTOLIC STRESS; NONINVASIVE DETERMINATION; MEASUREMENT SYSTEM; EJECTION FRACTION; PULSE PRESSURE; ARTERY; RISK; ECHOCARDIOGRAPHY; HYPERTROPHY;
D O I
10.7863/ultra.16.02031
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Objectives To investigate whether newly diagnosed untreated hypertensive patients show higher left ventricular (LV) contractility, as assessed by traditional echocardiographic indices and carotid wave intensity (WI) parameters, including amplitude of the peak during early (W1) and late systole (W2). Methods A total of 145 untreated hypertensive patients were compared with 145 age- and sex-matched normotensive subjects. They underwent comprehensive echocardiography and WI analysis. WI analysis was performed at the level of the common carotid artery. The diameter changes were the difference between the displacement of the anterior and posterior walls, with the cursors set to track the media-adventitia boundaries 2 cm proximal to the carotid bulb and calibrated by systolic and diastolic BP. Peak acceleration was derived from blood flow velocity measured by Doppler sonography with the range-gate positioned at the center of the vessel diameter. WI was based on the calculation of (dP/dt) X (dU/dt), where dP/ dt and dU/dt were the derivatives of BP (P) and velocity (U) with respect to time. One-point pulse wave velocity (PWVI3) and the interval between the R wave on ECG and the fast peak of WI (R-W1), using a high definition echo-tracking system implemented in the ultrasound machine (Aloka), were also derived. Results After adjustment for body weight, heart rate, and physical activity, the two groups had similar general characteristics and diastolic function. However, hypertensives showed significantly higher LV mass, LV ejection fraction (LVEF), circumferential and LV end-systolic stress, and one-point PWV as well as W1 (13.646 +/- 7.368 vs 9.308 +/- 4.675 mmHg m/s(3), P =.001) and W2 (4.289 +/- 2.017 vs 2.995 +/- 1.868 mmHg m/s', P =.001). Hypertensives were divided into tertiles according to LVEF: W1 (11.934 +/- 5.836 vs 11.576 +/- 5.857 vs 17.227 +/- 8.889 mmHg m/s(3), P <.0001) was higher in the highest LVEF textile along with relative wall thickness, midwall fractional shortening, endocardial fractional shortening, and R-W-1. Conclusions Newly diagnosed hypertensives show increased LVM and LV contractility, including carotid WI parameters and R-W, values, as compared with normotensive subjects, but no differences in LV diastolic function.
引用
收藏
页码:25 / 35
页数:11
相关论文
共 51 条
[41]   Systolic and diastolic blood pressure, pulse pressure, and mean arterial pressure as predictors of cardiovascular disease risk in men [J].
Sesso, HD ;
Stampfer, MJ ;
Rosner, B ;
Hennekens, CH ;
Gaziano, JM ;
Manson, JE ;
Glynn, RJ .
HYPERTENSION, 2000, 36 (05) :801-807
[42]   Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function [J].
Sohn, DW ;
Chai, IH ;
Lee, DJ ;
Kim, HC ;
Kim, HS ;
Oh, BH ;
Lee, MM ;
Park, YB ;
Choi, YS ;
Seo, JD ;
Lee, YW .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 30 (02) :474-480
[43]   BLOOD-PRESSURE, SYSTOLIC AND DIASTOLIC, AND CARDIOVASCULAR RISKS - UNITED-STATES POPULATION-DATA [J].
STAMLER, J ;
STAMLER, R ;
NEATON, JD .
ARCHIVES OF INTERNAL MEDICINE, 1993, 153 (05) :598-615
[44]   Relationship between the pressure and diameter of the carotid artery in humans [J].
Sugawara, M ;
Niki, K ;
Furuhata, H ;
Ohnishi, S ;
Suzuki, S .
HEART AND VESSELS, 2000, 15 (01) :49-51
[45]   Non-invasive one-point carotid wave intensity in a large group of healthy subjects [J].
Vriz, Olga ;
Zito, Concetta ;
di Bello, Vitantonio ;
La Carrubba, Salvatore ;
Driussi, Caterina ;
Carerj, Scipione ;
Bossone, Eduardo ;
Antonini-Canterin, Francesco .
HEART AND VESSELS, 2016, 31 (03) :360-369
[46]   Comparison of sequentially measured Aloka echo-tracking one-point pulse wave velocity with SphygmoCor carotid-femoral pulse wave velocity [J].
Vriz, Olga ;
Driussi, Caterina ;
La Carrubba, Salvatore ;
Di Bello, Vitantonio ;
Zito, Concetta ;
Carerj, Scipione ;
Antonini-Canterin, Francesco .
SAGE OPEN MEDICINE, 2013, 1
[47]   Carotid Artery Stiffness and Diastolic Function in Subjects without Known Cardiovascular Disease [J].
Vriz, Olga ;
Bossone, Eduardo ;
Bettio, Manola ;
Pavan, Daniela ;
Carerj, Scipione ;
Antonini-Canterin, Francesco .
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2011, 24 (08) :915-921
[48]   Systolic and diastolic blood pressure lowering as determinants of cardiovascular outcome [J].
Wang, JG ;
Staessen, JA ;
Franklin, SS ;
Fagard, R ;
Gueyffier, F .
HYPERTENSION, 2005, 45 (05) :907-913
[49]   Lifestyle, family history and progression of hypertension [J].
Winnicki, Mikolaj ;
Somers, Virend K. ;
Dorigatti, Francesca ;
Longo, Daniele ;
Santonastaso, Massimo ;
Mos, Lucio ;
Mattarei, Mauro ;
Pessina, Achille C. ;
Palatini, Paolo .
JOURNAL OF HYPERTENSION, 2006, 24 (08) :1479-1487
[50]   Age, Sex, and Hypertension-Related Remodeling Influences Left Ventricular Torsion Assessed by Tagged Cardiac Magnetic Resonance in Asymptomatic Individuals The Multi-Ethnic Study of Atherosclerosis [J].
Yoneyama, Kihei ;
Gjesdal, Ola ;
Choi, Eui-Young ;
Wu, Colin O. ;
Hundley, W. Gregory ;
Gomes, Antoinette S. ;
Liu, Chia-Ying ;
McClelland, Robyn L. ;
Bluemke, David A. ;
Lima, Joao A. C. .
CIRCULATION, 2012, 126 (21) :2481-2490