Acute Diarrhea in Dogs: Current Management and Potential Role of Dietary Polyphenols Supplementation

被引:22
作者
Candellone, Alessia [1 ]
Cerquetella, Matteo [2 ]
Girolami, Flavia [1 ]
Badino, Paola [1 ]
Odore, Rosangela [1 ]
机构
[1] Univ Turin, Dept Vet Sci, Largo Braccini 2, I-10095 Grugliasco, Italy
[2] Univ Camerino, Sch Biosci & Vet Med, Via Circonvallaz 93-95, I-62024 Matelica, Italy
关键词
acute diarrhea; dog; therapeutic management; dietary interventions; polyphenols supplementation; antibacterial resistance; INFLAMMATORY-BOWEL-DISEASE; EARLY ENTERAL NUTRITION; EXPERIMENTAL COLITIS; INTESTINAL PERMEABILITY; PHENOLIC-COMPOUNDS; HYDROGEN-PEROXIDE; OXIDATIVE STRESS; GUT MICROBIOTA; DOUBLE-BLIND; ANTIOXIDANT;
D O I
10.3390/antiox9080725
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Acute diarrhea is one of the most common reasons why pet owners seek veterinary care for their canine companions. In many cases, signs resolve spontaneously or with symptomatic therapy without a specific cause being discovered. However, life-threatening cases can occur. The etiology is complex, including infectious diseases (endoparasites, virus, bacteria, protozoa, fungal agents) by both zoonotic and non-zoonotic pathogens, dietary indiscretion, endocrine diseases, and stress (e.g., travel or environmental changes). In the last years, the role played by oxidative stress in the pathogenesis of acute and chronic enteropathies, independently from the initial noxa, has been highlighted by many researches in both humans and animals. As a result, a series of dietary antioxidant compounds have been studied for their potential use in the treatment of intestinal inflammation. This review summarizes the traditional therapeutic and nutritional options to manage canine acute diarrhea, highlighting the need to explore the role of oxidative stress and potential antioxidant supplementation, especially polyphenols, during acute diarrheic episodes.
引用
收藏
页码:1 / 17
页数:17
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