Three new norlignans from Glechoma longituba

被引：20
|
作者：
Zhu, Qiu-Fang [1 ]
Wang, Yong-Yi [1 ]
Jiang, Wei [1 ]
Qu, Hai-Bin [1 ]
机构：
[1] Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310058, Zhejiang, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2013年 / 15卷 / 03期
关键词：
Glechoma longituba; norlignans; glechomols AC;
D O I：
10.1080/10286020.2012.762640
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Three new norlignans, glechomols AC (13, respectively), together with a known compound, 4-ethylcatechol (4), were isolated from the ethyl acetate extract of Glechoma longituba (NaKai) Kupr. Their structures were elucidated by the detailed analysis of 1D and 2D NMR and HR-MS data. Glechomols AC were the first norlignans reported from genus Glechoma, and compound 4 was also isolated from genus Glechoma for the first time. Intracellular antioxidant assays showed that compounds 14 displayed significant protective effects on H2O2-induced cardiac cell injury.
引用
收藏
页码：258 / 264
页数：7
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