Metal-Ligand Cooperation Facilitates Bond Activation and Catalytic Hydrogenation with Zinc Pincer Complexes

被引：62

作者：

Rauch, Michael ^{[1
]}

Kar, Sayan ^{[1
]}

Kumar, Amit ^{[1
]}

Avram, Liat ^{[2
]}

Shimon, Linda J. W. ^{[2
]}

Milstein, David ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Organ Chem, IL-76100 Rehovot, Israel

[2] Weizmann Inst Sci, Dept Chem Res Support, IL-76100 Rehovot, Israel

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2020年 / 142卷 / 34期

基金：

欧洲研究理事会;

关键词：

ENANTIOSELECTIVE HYDROSILYLATION; COORDINATION CHEMISTRY; PNP; REACTIVITY; IMINES; DEHYDROGENATION; REDUCTION; ALUMINUM; BEARING; H-2;

D O I：

10.1021/jacs.0c05500

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of PNP zinc pincer complexes capable of bond activation via aromatization/dearomatization metal-ligand cooperation (MLC) were prepared and characterized. Reversible heterolytic N-H and H-H bond activation by MLC is shown, in which hemilability of the phosphorus linkers plays a key role. Utilizing this zinc pincer system, basefree catalytic hydrogenation of imines and ketones is demonstrated. A detailed mechanistic study supported by computation implicates the key role of MLC in facilitating effective catalysis. This approach offers a new strategy for (de)hydrogenation and other catalytic transformations mediated by zinc and other main group metals.

引用

页码：14513 / 14521

页数：9

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