Genome architecture and global gene regulation in bacteria: making progress towards a unified model?

被引:143
作者
Dorman, Charles J. [1 ]
机构
[1] Trinity Coll Dublin, Moyne Inst Prevent Med, Dept Microbiol, Dublin 2, Ireland
基金
爱尔兰科学基金会;
关键词
ESCHERICHIA-COLI CHROMOSOME; NUCLEOID-ASSOCIATED PROTEINS; SPATIAL-ORGANIZATION; H-NS; DNA; TRANSCRIPTION; DYNAMICS; SEQA; CONDENSATION; REPLICATION;
D O I
10.1038/nrmicro3007
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Data obtained with advanced imaging techniques, chromosome conformation capture methods, bioinformatics and molecular genetics, together with insights from polymer physics and mechanobiology, are helping to refine our understanding of the spatiotemporal organization of the bacterial nucleoid and its gene expression programmes. Here, l discuss the proposal that, in addition to DNA topology and nucleoid-associated proteins, gene regulation is an important organizing principle of nucleoid architecture.
引用
收藏
页码:349 / 355
页数:7
相关论文
共 72 条
[1]   Gene Amplification and Adaptive Evolution in Bacteria [J].
Andersson, Dan I. ;
Hughes, Diarmaid .
ANNUAL REVIEW OF GENETICS, 2009, 43 :167-195
[2]   Excess SeqA prolongs sequestration of oriC and delays nucleoid segregation and cell division [J].
Bach, T ;
Krekling, MA ;
Skarstad, K .
EMBO JOURNAL, 2003, 22 (02) :315-323
[3]   The Escherichia coli SMC Complex, MukBEF, Shapes Nucleoid Organization Independently of DNA Replication [J].
Badrinarayanan, Anjana ;
Lesterlin, Christian ;
Reyes-Lamothe, Rodrigo ;
Sherratt, David .
JOURNAL OF BACTERIOLOGY, 2012, 194 (17) :4669-4676
[4]   CHANGES IN THE LINKING NUMBER OF SUPERCOILED DNA ACCOMPANY GROWTH TRANSITIONS IN ESCHERICHIA-COLI [J].
BALKE, VL ;
GRALLA, JD .
JOURNAL OF BACTERIOLOGY, 1987, 169 (10) :4499-4506
[5]   ATP binding controls distinct structural transitions of Escherichia coli DNA gyrase in complex with DNA [J].
Basu, Aakash ;
Schoeffler, Allyn J. ;
Berger, James M. ;
Bryant, Zev .
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2012, 19 (05) :538-U105
[6]   Physical descriptions of the bacterial nucleoid at large scales, and their biological implications [J].
Benza, Vincenzo G. ;
Bassetti, Bruno ;
Dorfman, Kevin D. ;
Scolari, Vittore F. ;
Bromek, Krystyna ;
Cicuta, Pietro ;
Lagomarsino, Marco Cosentino .
REPORTS ON PROGRESS IN PHYSICS, 2012, 75 (07)
[7]   Spatial organization of a replicating bacterial chromosome [J].
Berlatzky, Idit Anna ;
Rouvinski, Alex ;
Ben-Yehuda, Sigal .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (37) :14136-14140
[8]   The complete genome sequence of Escherichia coli K-12 [J].
Blattner, FR ;
Plunkett, G ;
Bloch, CA ;
Perna, NT ;
Burland, V ;
Riley, M ;
ColladoVides, J ;
Glasner, JD ;
Rode, CK ;
Mayhew, GF ;
Gregor, J ;
Davis, NW ;
Kirkpatrick, HA ;
Goeden, MA ;
Rose, DJ ;
Mau, B ;
Shao, Y .
SCIENCE, 1997, 277 (5331) :1453-+
[9]   DNA supercoiling contributes to disconnect σs accumulation from σs-dependent transcription in Escherichia coli [J].
Bordes, P ;
Conter, A ;
Morales, V ;
Bouvier, J ;
Kolb, A ;
Gutierrez, C .
MOLECULAR MICROBIOLOGY, 2003, 48 (02) :561-571
[10]  
Brock T.D., 1990, The emergence of bacterial genetics