Occupational hazard is the important factor of making economic loss and affecting social stability. In order to manage the occupational hazard information, improve inspecting and managing skill of government, ensure the exchange and share of data between all level government department, a occupational hazard management information system used for enterprise, county, city, province and national department has been developed. With five levels of distribution storage structure, the system include basic data module, data management module, inspect information module, geography information module, decision support module, expert consultation module, accident investigating module, data synchronization module and training module. Based on occupational hazard index system, with TCP/IP wide area network, the system use network database (SQL server) and ASP, JAVA technology to develop, and implement 3-tier network software structure with B/S/W model. The system is useful for improving occupational hazard manage skill of China.