APPLICATIONS OF CALCIUM PHOSPHATE NANOPARTICLES IN POROUS HARD TISSUE ENGINEERING SCAFFOLDS

被引：29

作者：

Wang, Zhe ^{[1
]}

Tang, Zhurong ^{[1
]}

Qing, Fangzhu ^{[1
]}

Hong, Youliang ^{[1
]}

Zhang, Xingdong ^{[1
]}

机构：

[1] Sichuan Univ, Natl Engn Res Ctr Biomat, Chengdu 610064, Peoples R China

来源：

NANO | 2012年 / 7卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Calcium phosphate nanoparticles; tissue engineering; bone scaffold; porous structure; biomimetic; BETA-TRICALCIUM PHOSPHATE; SPRAYED HYDROXYAPATITE COATINGS; SOL-GEL TECHNIQUE; COMPOSITE SCAFFOLDS; NANO-HYDROXYAPATITE; NANOCRYSTALLINE HYDROXYAPATITE; NANOSTRUCTURED HYDROXYAPATITE; HYDROTHERMAL SYNTHESIS; TEMPLATE SYNTHESIS; CRYSTAL-GROWTH;

D O I：

10.1142/S1793292012300046

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

To repair bone defects, an important approach is to fabricate tissue engineering scaffolds as substitutions to replace auto-/allologous bones. Currently, processing a biomaterial into three-dimensional porous scaffolds and incorporating the calcium phosphate (Ca-P) nanoparticles into scaffolds profile two main characteristics of bone tissue engineering scaffolds. Based on this fact, in this paper we describe the design principles of the Ca-P nanoparticle-based and porous bone tissue engineering scaffolds. Then we summarize a variety of the Ca-P nanoparticle-based scaffolds, including discussion of the integration of the Ca-P nanoparticles with ceramics and polymers, followed by introduction of safety of the Ca-P nanoparticles in scaffolds.

引用

页数：18

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