Infantile Hemangiomas in the Head and Neck Region

被引:30
作者
Adams, Denise M. [1 ,2 ,3 ]
Ricci, Kiersten W. [1 ,2 ,3 ]
机构
[1] Boston Childrens Hosp, Vasc Anomalies Ctr, Div Hematol, 300 Longwood Ave, Boston, MA 02115 USA
[2] Boston Childrens Hosp, Oncol, 300 Longwood Ave, Boston, MA 02115 USA
[3] Cincinnati Childrens Hosp Med Ctr, Canc & Blood Dis Inst, Hemangioma & Vasc Malformat Ctr, Div Hematol, Cincinnati, OH 45229 USA
关键词
Infantile hemangioma; Focal; Segmental/regional/diffuse hemangioma; Hepatic hemangioma; Propranolol; Timolol; PHACE SYNDROME; CEREBRAL VASCULOPATHY; TOPICAL TIMOLOL; CLINICAL CHARACTERISTICS; VASCULAR MALFORMATIONS; ARTERIAL ANOMALIES; ENDOTHELIAL-CELLS; PROPRANOLOL; ASSOCIATION; MANAGEMENT;
D O I
10.1016/j.otc.2017.09.009
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Infantile hemangiomas (IHs) are benign vascular tumors of infancy most common in the region of the head and neck. Infantile hemangiomas are common; but they are extremely heterogeneous and cause a range of complications depending on their morphology, size, or location. Medical interventions for high-risk patients include topical and systemic therapies, including oral propranolol, which has revolutionized the management of IHs over the past recent years. In the following article, the authors aim to provide a review of the natural history, pathology, complications, syndromes, and medical management of infantile hemangioma.
引用
收藏
页码:77 / +
页数:13
相关论文
共 61 条
[11]   RCT of Timolol Maleate Gel for Superficial Infantile Hemangiomas in 5-to 24-Week-Olds [J].
Chan, Hsien ;
McKay, Catherine ;
Adams, Susan ;
Wargon, Orli .
PEDIATRICS, 2013, 131 (06) :E1739-E1747
[12]   Tooth Enamel Hypoplasia in PHACE Syndrome [J].
Chiu, Yvonne E. ;
Siegel, Dawn H. ;
Drolet, Beth A. ;
Hodgson, Brian D. .
PEDIATRIC DERMATOLOGY, 2014, 31 (04) :455-458
[13]   Placental hypoxia and neonatal haemangioma: clinical and histological observations [J].
Colonna, V. ;
Resta, L. ;
Napoli, A. ;
Bonifazi, E. .
BRITISH JOURNAL OF DERMATOLOGY, 2010, 162 (01) :208-209
[14]   Topical Timolol Maleate 0.5% for Infantile Hemangioma: Its Effectiveness Compared to Ultrapotent Topical Corticosteroids - A Single-Center Experience of 278 Cases [J].
Danarti, Retno ;
Ariwibowo, Lukman ;
Radiono, Sunardi ;
Budiyanto, Arief .
DERMATOLOGY, 2016, 232 (05) :566-571
[15]  
Darrow DH, 2015, PEDIATRICS, V136, pE1060, DOI 10.1542/peds.2015-2485
[16]   Diagnosis and Management of Infantile Hemangioma: Executive Summary [J].
Darrow, David H. ;
Greene, Arin K. ;
Mancini, Anthony J. ;
Nopper, Amy J. .
PEDIATRICS, 2015, 136 (04) :786-791
[17]   Does hypoxia play a role in infantile hemangioma? [J].
de Jong, Sophie ;
Itinteang, Tinte ;
Withers, Aaron H. J. ;
Davis, Paul F. ;
Tan, Swee T. .
ARCHIVES OF DERMATOLOGICAL RESEARCH, 2016, 308 (04) :219-227
[18]  
Di Maio L, 2011, IN VIVO, V25, P117
[19]   Hepatic vascular tumors [J].
Dickie, Belinda Hsi ;
Fishman, Steven J. ;
Azizkhan, Richard G. .
SEMINARS IN PEDIATRIC SURGERY, 2014, 23 (04) :168-172
[20]   Early stroke and cerebral vasculopathy in children with facial hemangiomas and PHACE association [J].
Drolet, BA ;
Dohil, M ;
Golomb, MR ;
Wells, R ;
Murowski, L ;
Tamburro, J ;
Sty, J ;
Friedlander, SF .
PEDIATRICS, 2006, 117 (03) :959-964