Nucleophilic trifluoromethylation tamed

被引：274

作者：

Prakash, GKS ^{[1
]}

Mandal, M ^{[1
]}

机构：

[1] Univ So Calif, Dept Chem, Loker Hydrocarbon Res Inst, Los Angeles, CA 90089 USA

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2001年 / 112卷 / 01期

关键词：

amides; amines; amino alcohols; enones; esters; nucleophilic trifluoromethylation; TMSCF3;

D O I：

10.1016/S0022-1139(01)00477-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The paper reviews our recent findings on the trifluoromethylation of organic compounds using TMSCF3. Direct preparation of trifluoromethylated ketones from esters, amides from alcohols and an-lines from imines is described. Trifluoromethylated amino alcohols are also prepared using a three-component condensation chemistry. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：123 / 131

页数：9

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