Absolute configuration of chlorojanerin, a chlorine-containing guaianolide from Centaurea scoparia

被引：6

作者：

Mattern, G ^{[1
]}

Weckert, E ^{[1
]}

Youssef, D ^{[1
]}

Frahm, AW ^{[1
]}

机构：

[1] UNIV FREIBURG,LEHRSTUHL PHARMAZEUT CHEM,D-79104 FREIBURG,GERMANY

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1996年 / 52卷

关键词：

D O I：

10.1107/S0108270196000741

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The title guaianolide, chlorojanerin [(1R,3S,4R,5S,6S,7R,8S)-4-chloromethyl-3,4-dihydroxy-8-(4- acryloyl)-1H,5H,6H,7H-guaia-10 (14),11(13)-dien-6,12-olide, C19H23ClO7], was obtained from the ethanol extracts of the air-dried aerial flowering parts of the Egyptian plant Centaurea scoparia Sieb. Its absolute configuration has been elucidated by X-ray analysis, which confirms the structure as a chlorine-containing guaianolide with the 4-hydroxymethacryloyl function at the C8 position, as previously proposed on the basis of H-1 NMR and CD spectral evidence.

引用

页码：1791 / 1793

页数：3

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