Photocaged permeability: a new strategy for controlled drug release

被引：36

作者：

Dcona, M. Michael ^{[1
,2
]}

Mitra, Deboleena ^{[1
,2
]}

Goehe, Rachel W. ^{[2
,3
]}

Gewirtz, David A. ^{[2
,3
]}

Lebman, Deborah A. ^{[2
,4
]}

Hartman, Matthew C. T. ^{[1
,2
]}

机构：

[1] Virginia Commonwealth Univ, Dept Chem, Richmond, VA 23284 USA

[2] Virginia Commonwealth Univ, Massey Canc Ctr, Richmond, VA 23298 USA

[3] Virginia Commonwealth Univ, Dept Pharmacol & Toxicol, Richmond, VA 23298 USA

[4] Virginia Commonwealth Univ, Dept Microbiol & Immunol, Richmond, VA 23298 USA

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 39期

关键词：

PHOTOCHEMICAL INTERNALIZATION; PHOTODYNAMIC THERAPY; PROTEIN-ACTIVITY; DOXORUBICIN; TECHNOLOGY; CHEMISTRY; LINKERS; MODEL;

D O I：

10.1039/c2cc30819c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Light is used to release a drug from a cell impermeable small molecule, uncloaking its cytotoxic effect on cancer cells.

引用

页码：4755 / 4757

页数：3

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