Gold Nanoparticle Based Plasmon Resonance Light-Scattering Method as a New Approach for Glycogen-Biomacromolecule Interactions

被引：28
作者：
Xiang, Minghui [1 ]
Xu, Xiao [1 ]
Liu, Feng [1 ]
Li, Na [1 ]
Li, Ke-An [1 ]
机构：
[1] Peking Univ, BNLMS, Key Lab Bioorgan Chem & Mol Engn, Minist Educ,Inst Analyt Chem,Coll Chem & Mol Engn, Beijing 100871, Peoples R China
来源：
JOURNAL OF PHYSICAL CHEMISTRY B | 2009年 / 113卷 / 09期
关键词：
PROTEIN-CARBOHYDRATE INTERACTION; IONIZATION MASS-SPECTROMETRY; CONCANAVALIN-A; GLYCONANOPARTICLES; AFFINITY; SIZE; OLIGOSACCHARIDES; CHROMATOGRAPHY; SPECTROSCOPY;
D O I：
10.1021/jp8065822
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
A model was developed for the interactions between glycogen and biomacromolecules by gold nanoparticle plasmon resonance light-scattering method. The interactions between glycogen and biomacromolecules can alter the aggregation status of gold nanoparticles, which produced intensity changes in plasmon resonance light-scattering. This is a sensitive method to study the interactions between glycogen and biomacromolecules from nano- to micromolar level. And it is also a simple method that measurement can be carried out with a common fluorospectrometer using label-free gold nanoparticles as the transducer.
引用
收藏
页码：2734 / 2738
页数：5
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