Extremely selective Mg(ClO4)2 mediated removal of Bpoc/Ddz moieties suitable for the solid phase peptide synthesis of thioxo peptides

被引：22

作者：

Wildemann, D ^{[1
]}

Drewello, M ^{[1
]}

Fischer, G ^{[1
]}

Schutkowski, M ^{[1
]}

机构：

[1] Max Planck Res Unit Enzymol Prot Folding, Halle, Germany

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 18期

关键词：

D O I：

10.1039/a905678e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Mg(ClO4)(2) in organic solvents acts as an extremely mild reagent for repetitive Bpoc/Ddz deprotection during solid phase peptide synthesis even in the presence of the acid labile thioxo amide moiety with excellent yields.

引用

页码：1809 / 1810

页数：2

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