Botulinum Toxin Injections in Musculoskeletal Disorders

被引:11
作者
Godoy, Ivan R. B. [1 ,2 ]
Donahue, Dean M. [2 ,3 ]
Torriani, Martin [1 ,2 ]
机构
[1] Massachusetts Gen Hosp, Div Musculoskeletal Imaging & Intervent, Boston, MA 02114 USA
[2] Harvard Med Sch, Boston, MA USA
[3] Massachusetts Gen Hosp, Dept Surg, Div Thorac Surg, Boston, MA 02114 USA
关键词
botulinum toxin; muscle injection; ultrasound; intervention; THORACIC OUTLET SYNDROME; RANDOMIZED CONTROLLED-TRIAL; PIRIFORMIS MUSCLE SYNDROME; RESISTANT CERVICAL DYSTONIA; CHRONIC PLANTAR FASCIITIS; PLACEBO-CONTROLLED TRIAL; LOW-BACK-PAIN; CEREBRAL-PALSY; DOUBLE-BLIND; A TOXIN;
D O I
10.1055/s-0036-1594284
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Botulinurn toxin (BTX) is used for multiple clinical indications due to its ability to induce temporary chemodenervation and muscle paralysis. This property has supported its application in treating a variety of musculoskeletal conditions, especially those involving muscular hyperactivity and contractures such as cerebral palsy and dystonia. However, off-label use of BTX injection in other musculoskeletal disorders is gaining increased acceptance, such as in neurogenic thoracic outlet syndrome, epicondylitis, and shoulder pain after stroke. This review discusses the mechanism of action, best practices, and current indications of BTX injections in the musculoskeletal system. We also discuss the state of the science regarding BTX injections for musculoskeletal disorders and the available evidence supporting its use.
引用
收藏
页码:441 / 452
页数:12
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