One-Pot Pseudo Five-Component Green Synthesis of Novel Bis-Betti Bases by the Mannich-Type Reaction

被引：10
作者：
Olyaei, Abolfazl [1 ]
Rezaei, Morteza [1 ]
机构：
[1] Payame Noor Univ, Dept Chem, Tehran, Iran
来源：
LETTERS IN ORGANIC CHEMISTRY | 2013年 / 10卷 / 05期
关键词：
Terephthaldehyde; heteroaryl amine; naphthol; bis-Betti base; solvent-free; Mannich; ENANTIOSELECTIVE ADDITION; CATALYST; AMINONAPHTHOLS; EFFICIENT; SOLVENT; DIETHYLZINC; LIGANDS;
D O I：
10.2174/1570178611310050002
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A mild, efficient and straightforward method has been developed for the synthesis of novel bis-Betti bases via a pseudo five-component, one-pot condensation reaction of heteroaryl amines, terephthaldehyde and naphthols under solvent-free conditions. The salient features of this protocol are: simple reaction procedure, shorter reaction time, high to excellent yields, avoidance of aqueous work-up, and column chromatographic separation.
引用
收藏
页码：311 / 316
页数：6
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