Enantiospecific synthesis of (+)-hyacinthacine A2

被引：42

作者：

Dewi-Wülfing, P ^{[1
]}

Blechert, S ^{[1
]}

机构：

[1] Tech Univ Berlin, Inst Chem, D-10623 Berlin, Germany

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 2006卷 / 08期

关键词：

olefin cross metathesis; dihydroxylation; hydrogenation; alkaloids; natural products;

D O I：

10.1002/ejoc.200500914

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report an efficient synthesis of (+)-hyacinthacine A(2) in six steps from (S)-N-Cbz-vinylgylcine. The key strategies were the olefin cross metathesis (CM), Sharpless asymmetric dihydroxylation, and a sequential double reductive cyclization. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006).

引用

页码：1852 / 1856

页数：5

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