An Evidence-Based Review of Early Intervention and Prevention of Posttraumatic Stress Disorder

被引:48
作者
Birur, Badari [1 ]
Moore, Norman C. [2 ]
Davis, Lori L. [1 ,3 ]
机构
[1] Univ Alabama Birmingham, Dept Psychiat, 1713 6th Ave South, Birmingham, AL 35210 USA
[2] East Tennessee State Univ, Dept Psychiat, Quillen Coll Med, Johnson City, TN 37614 USA
[3] VA Med Ctr, 3701 Loop Rd East, Tuscaloosa, AL 35404 USA
关键词
Early intervention; Prevention; PTSD; Acute stress disorder; Trauma; COGNITIVE-BEHAVIORAL THERAPY; RANDOMIZED CONTROLLED-TRIAL; 3-YEAR FOLLOW-UP; 3 BRIEF PROGRAMS; QUALITY-OF-LIFE; SECONDARY PREVENTION; TRAUMATIC INJURY; FACILITATING RECOVERY; ANXIETY DISORDERS; CONDITIONED FEAR;
D O I
10.1007/s10597-016-0047-x
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
We present an evidence-based review of post-trauma interventions used to prevent posttraumatic stress disorder (PTSD). Literature search of PubMed from 1988 to March 2016 using keywords "Early Intervention AND Prevention of PTSD" yielded 142 articles, of which 52 intervention studies and 6 meta-analyses were included in our review. Trauma-focused cognitive behavioral therapy and modified prolonged exposure delivered within weeks of a potentially traumatic event for people showing signs of distress have the most evidence in the treatment of acute stress and early PTSD symptoms, and the prevention of PTSD. Even though several pharmacological agents have been tried, only hydrocortisone prior to high-risk surgery, severe traumatic injury, or during acute sepsis has adequate evidence for effectiveness in the reduction of acute stress symptoms and prevention of PTSD. There is an urgent need to determine the best targets for interventions after trauma to accelerate recovery and prevent PTSD.
引用
收藏
页码:183 / 201
页数:19
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