Correlation between 24-hour ambulatory systolic blood pressure and brachial-ankle pulse wave velocity: higher correlation 24-h with baPWV

Objective: Brachial ankle pulse wave velocity (baPWV) is a sensitive indicator of arterial stiffness. Few studies correlated cumulative systolic blood pressure (SBP) with arterial stiffness. Evidence underlying the factors related to baPWV in the clinical SBP, cumulative SBP and 24 h ambulatory SBP (24 h ABPM) is unavailable. This study was aimed to explore the correlation between cumulative, 24-h ambulatory systolic BP and brachial-ankle pulse wave velocity. Methods: The medical examination was administered to participants who were working and retired employees of the Kailuan community in Tangshan city (China). Relevant data were collected from 2006 to 2007, 2008 to 2009, and 2010 to 2011. We randomly selected participants aged >= 60 years and retired from the Tangshan Kailuan community in the third examination. Finally, a total of 2,464 eligible participants were enrolled for the 24-h ambulatory systolic BP (ABPM) and baPWV measurements. Multiple linear and logistic regression were used to quantify the effects of clinical, cumulative, 24-h, daytime, and nocturnal systolic BP on baPWV. Results: Of the 2,464 participants, 787 were subjected to statistical analysis (average age 67. 45, male, 62.2%). In fully adjusted models, the baPWV values increased by 178.40, 87.74, 149.39, 143.45, 137.58 cm/s for each additional 1-SD of clinical, cumulative, 24-h, diurnal and nocturnal systolic BP. Similar adjusted logistic-regression analyses showed that the OR values (95% CI) of baPWV were 2.21 (1.96 similar to 2.88), 1.71 (1.34 similar to 2.17), 0.96 (0.66 similar to 1.40), and 1.81 (1.24 similar to 2.46), respectively, for each additional SD (interaction term > 0.05). Conclusion: The 24-h, and nocturnal SBP exhibited significantly higher correlation with baPWV than cumulative SBP.