Assessment of interleukin-1, interleukin-6, and tumor necrosis factor- levels in the peri-implant sulcular fluid among waterpipe (narghile) smokers and never-smokers with peri-implantitis

被引：64
作者：
Abduljabbar, Tariq [1 ]
Akram, Zohaib [2 ]
Vohra, Fahim [1 ]
Warnakulasuriya, Saman [3 ,4 ]
Javed, Fawad [5 ]
机构：
[1] King Saud Univ, Dept Prosthet Dent Sci, Coll Dent, Riyadh, Saudi Arabia
[2] Ziauddin Univ, Dept Periodontol, Fac Dent, Karachi, Pakistan
[3] Kings Coll London, Dept Oral Med, London, England
[4] Kings Coll London, WHO Collaborating Ctr Oral Canc, London, England
[5] Univ Rochester, Eastman Inst Oral Hlth, Dept Gen Dent, 625 Elmwood Ave, Rochester, NY 14620 USA
来源：
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH | 2018年 / 20卷 / 02期
关键词：
alveolar bone loss; cytokine; inflammation; peri-implant diseases; smoking;
D O I：
10.1111/cid.12557
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
BackgroundIt is hypothesized that levels of interleukin (IL)-1, IL-6 and tumor necrosis factor (TNF)- are significantly higher in the peri-implant sulcular fluid (PISF) of waterpipe-smokers (WS) compared with never-smokers with peri-implantitis. PurposeThe aim of the present convenience sample case-control study was to compare the levels of IL-6, IL-1, and TNF- in the PISF of WS and never-smokers with peri-implantitis. Materials and MethodsDemographic data was collected using a questionnaire. Peri-implant probing depth (PPD) was measured and crestal bone loss (CBL) was measured on digital bitewing radiographs. PISF samples were collected using paper strips and the collected PISF volume was determined. levels of IL-6, IL-1, and TNF- were measured using enzyme linked immunosorbent assay. Study sample-size was estimated and statistical analysis was performed. P values less than .05 were considered statistically significant. ResultsSixty-six individuals (33 individuals in group-1 and 33 in group-2) were included. In groups 1 and 2, 41 and 44 implants, respectively were placed. The mean total PPD (P<.001) and peri-implant CBL (P<.001) was statistically significantly higher around implants affected by peri-implantitis in group-1 compared with group-2. The PISF volume (P<.05) collected and levels of IL-1 (P<.01), IL-6 (P<.01), and TNF- (P<.01) were statistically significantly higher among individuals in group-1 compared with group-2. ConclusionWS with peri-implantitis present increased expression of local proinflammatory cytokines in the PISF than never-smokers.
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收藏
页码：144 / 150
页数：7
相关论文
共 39 条
[31]   Cytokines expression in saliva and peri-implant crevicular fluid of patients with peri-implant disease [J].
Persegani Olivar Fonseca, Fabio Jose ;
Moraes Junior, Mario ;
Veras Lourenco, Eduardo Jose ;
Teles, Daniel de Moraes ;
Figueredo, Carlos Marcelo .
CLINICAL ORAL IMPLANTS RESEARCH, 2014, 25 (02) :E68-E72
[32]   Biomarker levels in gingival crevicular fluid of generalized aggressive periodontitis patients after non-surgical periodontal treatment [J].
Romano, Federica ;
Bongiovanni, Loretta ;
Bianco, Laura ;
Di Scipio, Federica ;
Yang, Zhiqian ;
Sprio, Andrea Elio ;
Berta, Giovanni Nicolao ;
Aimetti, Mario .
CLINICAL ORAL INVESTIGATIONS, 2018, 22 (02) :1083-1092
[33]   Water pipe tobacco smoking in the United States: Findings from the National Adult Tobacco Survey [J].
Salloum, Ramzi G. ;
Thrasher, James F. ;
Kates, Frederick R. ;
Maziak, Wasim .
PREVENTIVE MEDICINE, 2015, 71 :88-93
[34]   Marginal bone loss and dental implant failure may be increased in smokersQuestion: Is there a difference in marginal bone loss or implant failure rates between smokers and non-smokers, depending on the follow-up period? [J].
Analia Veitz-Keenan .
Evidence-Based Dentistry, 2016, 17 (1) :6-7
[35]   Waterpipe smoking, oral cancer and other oral health effectsQuestions: Is waterpipe tobacco smoking possibly associated with deleterious health outcomes? [J].
Saman Warnakulasuriya .
Evidence-Based Dentistry, 2011, 12 (2) :44-45
[36]   The effects of waterpipe tobacco smoking on health outcomes: an updated systematic review and meta-analysis [J].
Waziry, Reem ;
Jawad, Mohammed ;
Ballout, Rami A. ;
Al Akel, Mohammad ;
Akl, Elie A. .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2017, 46 (01) :32-43
[37]   Advanced Glycation End Products Upregulate the Endoplasmic Reticulum Stress in Human Periodontal Ligament Cells [J].
Xu, Jie ;
Xiong, Ming ;
Huang, Bin ;
Chen, Huangqin .
JOURNAL OF PERIODONTOLOGY, 2015, 86 (03) :440-447
[38]   Peri-implant crevicular fluid biomarkers as discriminants of peri-implant health and disease [J].
Zani, Sabrina Rebollo ;
Moss, Kevin ;
Shibli, Jamil Awad ;
Teixeira, Eduardo Rolim ;
Mairink, Renata de Oliveira ;
Onuma, Tatiana ;
Feres, Magda ;
Teles, Ricardo Palmier .
JOURNAL OF CLINICAL PERIODONTOLOGY, 2016, 43 (10) :825-832
[39]   Definition and prevalence of peri-implant diseases [J].
Zitzmann, Nicola U. ;
Berglundh, Tord .
JOURNAL OF CLINICAL PERIODONTOLOGY, 2008, 35 :286-291
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