Assessment of interleukin-1, interleukin-6, and tumor necrosis factor- levels in the peri-implant sulcular fluid among waterpipe (narghile) smokers and never-smokers with peri-implantitis

被引：64
作者：
Abduljabbar, Tariq [1 ]
Akram, Zohaib [2 ]
Vohra, Fahim [1 ]
Warnakulasuriya, Saman [3 ,4 ]
Javed, Fawad [5 ]
机构：
[1] King Saud Univ, Dept Prosthet Dent Sci, Coll Dent, Riyadh, Saudi Arabia
[2] Ziauddin Univ, Dept Periodontol, Fac Dent, Karachi, Pakistan
[3] Kings Coll London, Dept Oral Med, London, England
[4] Kings Coll London, WHO Collaborating Ctr Oral Canc, London, England
[5] Univ Rochester, Eastman Inst Oral Hlth, Dept Gen Dent, 625 Elmwood Ave, Rochester, NY 14620 USA
来源：
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH | 2018年 / 20卷 / 02期
关键词：
alveolar bone loss; cytokine; inflammation; peri-implant diseases; smoking;
D O I：
10.1111/cid.12557
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
BackgroundIt is hypothesized that levels of interleukin (IL)-1, IL-6 and tumor necrosis factor (TNF)- are significantly higher in the peri-implant sulcular fluid (PISF) of waterpipe-smokers (WS) compared with never-smokers with peri-implantitis. PurposeThe aim of the present convenience sample case-control study was to compare the levels of IL-6, IL-1, and TNF- in the PISF of WS and never-smokers with peri-implantitis. Materials and MethodsDemographic data was collected using a questionnaire. Peri-implant probing depth (PPD) was measured and crestal bone loss (CBL) was measured on digital bitewing radiographs. PISF samples were collected using paper strips and the collected PISF volume was determined. levels of IL-6, IL-1, and TNF- were measured using enzyme linked immunosorbent assay. Study sample-size was estimated and statistical analysis was performed. P values less than .05 were considered statistically significant. ResultsSixty-six individuals (33 individuals in group-1 and 33 in group-2) were included. In groups 1 and 2, 41 and 44 implants, respectively were placed. The mean total PPD (P<.001) and peri-implant CBL (P<.001) was statistically significantly higher around implants affected by peri-implantitis in group-1 compared with group-2. The PISF volume (P<.05) collected and levels of IL-1 (P<.01), IL-6 (P<.01), and TNF- (P<.01) were statistically significantly higher among individuals in group-1 compared with group-2. ConclusionWS with peri-implantitis present increased expression of local proinflammatory cytokines in the PISF than never-smokers.
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收藏
页码：144 / 150
页数：7
相关论文
共 39 条
[1]   The prevalence of waterpipe tobacco smoking among the general and specific populations: a systematic review [J].
Akl, Elie A. ;
Gunukula, Sameer K. ;
Aleem, Sohaib ;
Obeid, Rawad ;
Abou Jaoude, Philippe ;
Honeine, Roland ;
Irani, Jihad .
BMC PUBLIC HEALTH, 2011, 11
[2]   Soft tissue changes and crestal bone loss around platform-switched implants placed at crestal and subcrestal levels: 36-month results from a prospective split-mouth clinical trial [J].
Al Amri, Mohammad D. ;
Al-Johany, Sulieman S. ;
Al Baker, Abdulaziz M. ;
Al Rifaiy, Mohammad Q. ;
Abduljabbar, Tariq S. ;
Al-Kheraif, Abdulaziz A. .
CLINICAL ORAL IMPLANTS RESEARCH, 2017, 28 (11) :1342-1347
[3]   Comparison of clinical and radiographic status around dental implants placed in patients with and without prediabetes: 1-year follow-up outcomes [J].
Al Amri, Mohammad D. ;
Abduljabbar, Tariq S. ;
Al-Kheraif, Abdulaziz A. ;
Romanos, Georgios E. ;
Javed, Fawad .
CLINICAL ORAL IMPLANTS RESEARCH, 2017, 28 (02) :231-235
[4]   Comparison of peri-implant clinical and radiographic inflammatory parameters among cigarette and waterpipe (narghile) smokers and never-smokers [J].
ALHarthi, Shatha Subhi ;
BinShabaib, Munerah Saleh ;
Ahmed, Hameeda Bashir ;
Mehmood, Abid ;
Khan, Junad ;
Javed, Fawad .
JOURNAL OF PERIODONTOLOGY, 2018, 89 (02) :213-218
[5]   Impact of heavy smoking on the clinical, microbiological and immunological parameters of patients with dental implants: a prospective cross-sectional study [J].
Ata-Ali, Javier ;
Juan Flichy-Fernandez, Antonio ;
Alegre-Domingo, Teresa ;
Ata-Ali, Fadi ;
Penarrocha-Diago, Miguel .
JOURNAL OF INVESTIGATIVE AND CLINICAL DENTISTRY, 2016, 7 (04) :401-409
[6]   Salivary cytokine levels in early gingival inflammation [J].
Belstrom, Daniel ;
Damgaard, Christian ;
Kononen, Eija ;
Gursoy, Mervi ;
Holmstrup, Palle ;
Gursoy, Ulvi Kahraman .
JOURNAL OF ORAL MICROBIOLOGY, 2017, 9
[7]   The Effect of Waterpipe Smoking on Periodontal Health [J].
Bibars, Abdel Rahim M. ;
Obeidat, Suhair R. ;
Khader, Yousef ;
Mahasneh, Arwa M. ;
Khabour, Omar F. .
ORAL HEALTH & PREVENTIVE DENTISTRY, 2015, 13 (03) :253-259
[8]   Serum soluble receptor for advanced glycation end products (sRAGE) is independently associated with cigarette smoking in non-diabetic healthy subjects [J].
Biswas, Subrata K. ;
Mudi, Sonchita R. ;
Mollah, Forhadul H. ;
Bierhaus, Angelika ;
Arslan, M. Iqbal .
DIABETES & VASCULAR DISEASE RESEARCH, 2013, 10 (04) :380-382
[9]   Smoking and dental implants: A systematic review and meta-analysis [J].
Chrcanovic, Bruno Ramos ;
Albrektsson, Tomas ;
Wennerberg, Ann .
JOURNAL OF DENTISTRY, 2015, 43 (05) :487-498
[10]   Frequency of periodontal pathogens in equivalent peri-implant and periodontal clinical statuses [J].
Cortelli, Sheila Cavalca ;
Cortelli, Jose Roberto ;
Romeiro, Rogerio Lima ;
Costa, Fernando Oliveira ;
Aquino, Davi Romeiro ;
Orzechowski, Paulo Roberto ;
Araujo, Vera Cavalcanti ;
Duarte, Poliana Mendes .
ARCHIVES OF ORAL BIOLOGY, 2013, 58 (01) :67-74
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