Mechanical properties of PNIPAM based hydrogels: A review

被引:534
作者
Haq, Muhammad Abdul [1 ,2 ]
Su, Yunlan [1 ]
Wang, Dujin [1 ]
机构
[1] Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Engn Plast, Inst Chem, Beijing 100190, Peoples R China
[2] Univ Karachi, Dept Food Sci & Technol, Lab Food Engn, Karachi, Pakistan
来源
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2017年 / 70卷
关键词
Poly(N-isopropylacrylamide); Hydrogel; Smart material; Mechanical properties; POLYMER NETWORK HYDROGELS; INDUCED PHASE-TRANSITION; POLY(N-ISOPROPYLACRYLAMIDE) (PNIPAM)-GRAFTED GELATIN; ARTIFICIAL EXTRACELLULAR-MATRIX; N-ISOPROPYL ACRYLAMIDE; IMPROVED RESPONSE RATE; SEMI-IPN HYDROGELS; NANOCOMPOSITE HYDROGELS; INTERPENETRATING NETWORKS; ISOPROPYLACRYLAMIDE HYDROGELS;
D O I
10.1016/j.msec.2016.09.081
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Materials which adjust their properties in response to environmental factors such as temperature, pH and ionic strength are rapidly evolving and known as smart materials. Hydrogels formed by smart polymers have various applications. Among the smart polymers, thermoresponsive polymer poly(N-isopropylacrylamide)(PNIPAM) is very important because of its well defined structure and property specially its temperature response is closed to human body and can be finetuned as well. Mechanical properties are critical for the performance of stimuli responsive hydrogels in diverse applications. However, native PNIPAM hydrogels are very fragile and hardly useful for any practical purpose. Intense researches have been done in recent decade to enhance the mechanical features of PNIPAM hydrogel. In this review, several strategies including interpenetrating polymer network (IPN), double network (DN), nanocomposite (NC) and slide ring (SR) hydrogels are discussed in the context of PNIPAM hydrogel. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码:842 / 855
页数:14
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