Liposome-Gold Nanorod Hybrids for High-Resolution Visualization Deep in Tissues

被引：71
作者：
Lozano, Neus [2 ]
Al-Jamal, Wafa' T. [2 ]
Taruttis, Adrian [1 ]
Beziere, Nicolas [1 ]
Burton, Neal C. [1 ]
Van den Bossche, Jeroen [2 ]
Mazza, Mariarosa [2 ]
Herzog, Eva [1 ]
Ntziachristos, Vasilis [1 ]
Kostarelos, Kostas [2 ]
机构：
[1] Tech Univ Munich, IBMI, Helmholtz Zentrum Munich, Munich, Germany
[2] UCL, Sch Pharm, Ctr Drug Delivery Res, Nanomed Lab, London WC1N 1AX, England
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 134卷 / 32期
关键词：
RELEASE; DRUG;
D O I：
10.1021/ja304499q
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.
引用
收藏
页码：13256 / 13258
页数：3
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