Rapid simultaneous measurement of multiple cytokines in childhood oncology patients with febrile neutropenia: increased interleukin (IL)-8 or IL-5 correlates with culture-positive infection

被引:21
作者
Hodge, G [1 ]
Osborn, M
Hodge, S
Nairn, J
Tapp, H
Kirby, M
Sepulveda, H
Morgan, E
Revesz, T
Zola, H
机构
[1] Womens & Childrens Hosp, Haematol Oncol Dept, Adelaide, SA, Australia
[2] Womens & Childrens Hosp, Child Hlth Res Inst, Adelaide, SA, Australia
[3] Royal Adelaide Hosp, Thorac Dept, Adelaide, SA 5000, Australia
[4] Womens & Childrens Hosp, Renal Dept, Adelaide, SA, Australia
[5] BD Biosci Pharmingen, San Diego, CA USA
关键词
febrile neutropenia; infection; interleukin-5; interleukin-8;
D O I
10.1111/j.1365-2141.2005.05870.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:247 / 248
页数:3
相关论文
共 5 条
[1]   Interleukin 6, but not tumour necrosis factor-alpha, is a good predictor of severe infection in febrile neutropenic and non-neutropenic children with malignancy [J].
Abrahamsson, J ;
Pahlman, M ;
Mellander, L .
ACTA PAEDIATRICA, 1997, 86 (10) :1059-1064
[2]   An analysis of interleukin-8, interleukin-6 and C-reactive protein serum concentrations to predict fever, gram-negative bacteremia and complicated infection in neutropenic cancer patients [J].
Engel, A ;
Mack, E ;
Kern, P ;
Kern, WV .
INFECTION, 1998, 26 (04) :213-221
[3]   A double-blind comparison of empirical oral and intravenous antibiotic therapy for low-risk febrile patients with neutropenia during cancer chemotherapy [J].
Freifeld, A ;
Marchigiani, D ;
Walsh, T ;
Chanock, S ;
Lewis, L ;
Hiemenz, J ;
Hiemenz, S ;
Hicks, JE ;
Gill, V ;
Steinberg, SM ;
Pizzo, PP .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (05) :305-311
[4]   Rapid simultaneous measurement of multiple cytokines using 100 μl sample volumes -: association with neonatal sepsis [J].
Hodge, G ;
Hodge, S ;
Haslam, R ;
McPhee, A ;
Sepulveda, H ;
Morgan, E ;
Nicholson, I ;
Zola, H .
CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2004, 137 (02) :402-407
[5]   A pilot study of outpatient management of febrile neutropenic children with cancer at low risk of bacteremia [J].
Mustafa, MM ;
Aquino, VM ;
Pappo, A ;
Tkaczewski, I ;
Buchanan, GR .
JOURNAL OF PEDIATRICS, 1996, 128 (06) :847-849