Treatment Outcomes of Endoscopic Submucosal Dissection for Adenocarcinoma Originating from Long-Segment Barrett's Esophagus versus Short-Segment Barrett's Esophagus

被引：21

作者：

Shimizu, Tomoki ^{[1
]}

Fujisaki, Junko ^{[1
]}

Omae, Masami ^{[1
]}

Yamasaki, Akira ^{[1
]}

Horiuchi, Yusuke ^{[1
]}

Ishiyama, Akiyoshi ^{[1
]}

Yoshio, Toshiyuki ^{[1
]}

Hirasawa, Toshiaki ^{[1
]}

Yamamoto, Yorimasa ^{[1
]}

Tsuchida, Tomohiro ^{[1
]}

机构：

[1] Canc Inst Hosp, Dept Gastroenterol, Tokyo, Japan

来源：

DIGESTION | 2018年 / 97卷 / 04期

关键词：

Esophageal neoplasms; Barrett esophagus; Treatment outcome; Endoscopic mucosal resection; Narrow band imaging; HIGH-GRADE DYSPLASIA; MUCOSAL RESECTION; RADIOFREQUENCY ABLATION; CLINICAL-OUTCOMES; CANCER; RECURRENCE; NEOPLASIA; EFFICACY; THERAPY; SAFETY;

D O I：

10.1159/000486197

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background: In recent years, effective outcomes of endoscopic submucosal dissection (ESD) for esophagogastric junction cancer including short-segment Barrett's esophagus (SSBE) cancer have been reported. However, the efficacy of ESD for long-segment Barrett's esophagus (LSBE) cancer is unknown. Aim: To clarify the treatment outcomes of ESD for LSBE cancer versus SSBE cancer. Methods: A total of 86 patients with 91 superficial Barrett's esophageal adenocarcinomas who underwent ESD were enrolled; of these, 68 had underlying SSBE and 18 had LSBE. Procedure outcomes and prognosis were compared. Results: There was no significant difference in age and tumor diameter among patients. The only complication observed was stricture, but it was not significant (2 vs. 9%). No significant difference was observed in the negative horizontal margin rates (94.1 vs. 95.7%), R0 resection rates (83.8 vs. 82.6%), curative resection rates (72.1 vs. 73.9%), and noncurative factors. Both LSBE and SSBE cancer showed favorable 3-year overall survival rates (95.0 vs. 94.4%) in the median observation period of 28.5 months. Conclusions: ESD for LSBE cancer achieved procedure outcomes and short-term prognosis comparable to SSBE. ESD has the potential to be an effective therapeutic option for esophageal neoplasms in patients with LSBE. (C) 2018 S. Karger AG, Basel

引用

页码：316 / 323

页数：8

共 28 条

[1] Clinical outcome in patients treated with endoscopic submucosal dissection for superficial Barrett's neoplasia [J].

Chevaux, Jean Baptiste ;

Piessevaux, Hubert ;

Jouret-Mourin, Anne ;

Yeung, Ralph ;

Danse, Etienne ;

Deprez, Pierre H. .

ENDOSCOPY, 2015, 47 (02) :103-112

[2] Efficacy and safety outcomes of multimodal endoscopic eradication therapy in Barrett's esophagus-related neoplasia: a systematic review and pooled analysis [J].

Desai, Madhav ;

Saligram, Shreyas ;

Gupta, Neil ;

Vennalaganti, Prashanth ;

Bansal, Ajay ;

Choudhary, Abhishek ;

Vennelaganti, Sreekar ;

He, Jianghua ;

Titi, Mohammad ;

Maselli, Roberta ;

Qumseya, Bashar ;

Olyaee, Mojtaba ;

Waxman, Irwing ;

Repici, Alessandro ;

Hassan, Cesare ;

Sharma, Prateek .

GASTROINTESTINAL ENDOSCOPY, 2017, 85 (03) :482-+

[3] Recurrence of Esophageal Intestinal Metaplasia After Endoscopic Mucosal Resection and Radiofrequency Ablation of Barrett's Esophagus: Results From a US Multicenter Consortium [J].

Gupta, Milli ;

Iyer, Prasad G. ;

Lutzke, Lori ;

Gorospe, Emmanuel C. ;

Abrams, Julian A. ;

Falk, Gary W. ;

Ginsberg, Gregory G. ;

Rustgi, Anil K. ;

Lightdale, Charles J. ;

Wang, Timothy C. ;

Fudman, David I. ;

Poneros, John M. ;

Wang, Kenneth K. .

GASTROENTEROLOGY, 2013, 145 (01) :79-+

[4] Single center experience of endoscopic submucosal dissection (ESD) in early BarrettA′s adenocarcinoma [J].

Hoebel, S. ;

Dautel, P. ;

Baumbach, R. ;

Oldhafer, K-J. ;

Stang, A. ;

Feyerabend, B. ;

Yahagi, N. ;

Schrader, C. ;

Faiss, S. .

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2015, 29 (06) :1591-1597

[5] Endoscopic Submucosal Dissection and Endoscopic Mucosal Resection for Non-Ampullary Superficial Duodenal Tumor [J].

Hoteya, Shu ;

Furuhata, Tsukasa ;

Takahito, Toba ;

Fukuma, Yumiko ;

Suzuki, Yugo ;

Kikuchi, Daisuke ;

Mitani, Toshifumi ;

Matsui, Akira ;

Yamashita, Satoshi ;

Nomura, Kosuke ;

Kuribayashi, Yasutaka ;

Iizuka, Toshiro ;

Kaise, Mitsuru .

DIGESTION, 2017, 95 (01) :36-42

[6] Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus [J].

Hulscher, JBF ;

van Sandick, JW ;

de Boer, AGEM ;

Wijnhoven, BPL ;

Tijssen, JGP ;

Fockens, P ;

Stalmeier, PFM ;

ten Kate, FJW ;

van Dekken, H ;

Obertop, H ;

Tilanus, HW ;

van Lanschot, JJB .

NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (21) :1662-1669

[7] Risk of metastasis in adenocarcinoma of the esophagus: a multicenter retrospective study in a Japanese population [J].

Ishihara, Ryu ;

Oyama, Tsuneo ;

Abe, Seiichiro ;

Takahashi, Hiroaki ;

Ono, Hiroyuki ;

Fujisaki, Junko ;

Kaise, Mitsuru ;

Goda, Kenichi ;

Kawada, Kenro ;

Koike, Tomoyuki ;

Takeuchi, Manabu ;

Matsuda, Rie ;

Hirasawa, Dai ;

Yamada, Masayoshi ;

Kodaira, Junichi ;

Tanaka, Masaki ;

Omae, Masami ;

Matsui, Akira ;

Kanesaka, Takashi ;

Takahashi, Akiko ;

Hirooka, Shinichi ;

Saito, Masahiro ;

Tsuji, Yosuke ;

Maeda, Yuki ;

Yamashita, Hiroharu ;

Oda, Ichiro ;

Tomita, Yasuhiko ;

Matsunaga, Takashi ;

Terai, Shuji ;

Ozawa, Soji ;

Kawano, Tatsuyuki ;

Seto, Yasuyuki .

JOURNAL OF GASTROENTEROLOGY, 2017, 52 (07) :800-808

[8] Japanese Classification of Esophageal Cancer, 11th Edition: part I [J].

Japan Esophageal Society .

ESOPHAGUS, 2017, 14 (01) :1-36

[9] Clinical outcomes of endoscopic submucosal dissection for superficial Barrett's adenocarcinoma [J].

Kagemoto, Kenichi ;

Oka, Shiro ;

Tanaka, Shinji ;

Miwata, Tomohiro ;

Urabe, Yuji ;

Sanomura, Yoji ;

Yoshida, Shigeto ;

Hiyama, Toru ;

Arihiro, Koji ;

Chayama, Kazuaki .

GASTROINTESTINAL ENDOSCOPY, 2014, 80 (02) :239-245

[10] Investigation of the freely available easy-to-use software 'EZR' for medical statistics [J].

Kanda, Y. .

BONE MARROW TRANSPLANTATION, 2013, 48 (03) :452-458

← 1 2 3 →