Steroids and anthraquinones from the deep-sea-derived fungus Aspergillus nidulans MCCC 3A00050

被引:9
作者
Xing, Cui-Ping [1 ]
Wu, Jia [2 ]
Xia, Jin-Mei [1 ]
Fan, Shao-Qiang [1 ]
Yang, Xian-Wen [1 ]
机构
[1] Minist Nat Resources, Inst Oceanog 3, Key Lab Marine Biogenet Resources, South China Sea Bioresource Exploitat & Utilizat, Xiamen 361005, Peoples R China
[2] Capital Med Univ, Yanjing Med Coll, 4 Dadong Rd, Beijing 101300, Peoples R China
基金
中国国家自然科学基金;
关键词
Aspergillus nidulans; Deep-sea; Steroids; Anthraquinones; ENDOPHYTIC FUNGUS; SECONDARY METABOLITES; A-D; VERSICOLOR; DERIVATIVES; STRAIN; ALKALOIDS; CULTURE;
D O I
10.1016/j.bse.2018.12.012
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Aspergillus nidulans MCCC 3A00050 was isolated from a deep-sea sediment sample of the western Pacific Ocean. A systematic investigation on its chemical constituents led to the isolation of 19 compounds, including 13 steroids (1-13), four anthraquinones (14-17), one phenolics (18), and one chromanone (19). For the first time, three diosgenins (1-3) were isolated from fungi, three ergosterols (4-6) from the genus of Aspergillus, while other 11 miscellaneous compounds (7-11 and 14-19) from the species of Aspergillus nidulans. The isolation of diosgenins (1-3) and ergosterols (4-6) might be used as chemotaxonomic markers for the genus of Aspergillus and the species of Aspergillus nidulans, respectively.
引用
收藏
页码:103 / 105
页数:3
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