Pulsed magnetization transfer imaging: Evaluation of technique

被引:38
作者
Graham, SJ
Henkelman, RM
机构
[1] Univ Toronto, Dept Med Biophys, Toronto, ON, Canada
[2] Univ Toronto, Dept Med Imaging, Toronto, ON, Canada
[3] Sunnybrook & Womens Coll, Hlth Sci Ctr, Dept Imaging & Bioengn Res, Toronto, ON M4N 3M5, Canada
关键词
brain; abnormalities; MR; white matter; magnetic resonance (MR); magnetization transfer contrast; sclerosis; multiple;
D O I
10.1148/radiology.212.3.r99se05903
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
With use of an established physical model, numeric simulations were performed to evaluate current imaging protocols for the two primary applications of magnetization transfer: cerebral magnetic resonance angiography and neuroimaging of white matter disease. The authors found that the current technique is appropriate in the former but suboptimal in the latter. Further clinical investigations could potentially improve magnetization protocols for neuroimaging.
引用
收藏
页码:903 / 910
页数:8
相关论文
共 37 条
[1]   IMPROVED MR-ANGIOGRAPHY - MAGNETIZATION-TRANSFER SUPPRESSION WITH VARIABLE FLIP ANGLE EXCITATION AND INCREASED RESOLUTION [J].
ATKINSON, D ;
BRANTZAWADZKI, M ;
GILLAN, G ;
PURDY, D ;
LAUB, G .
RADIOLOGY, 1994, 190 (03) :890-894
[2]   EFFECTS OF DIFFUSION ON FREE PRECESSION IN NUCLEAR MAGNETIC RESONANCE EXPERIMENTS [J].
CARR, HY ;
PURCELL, EM .
PHYSICAL REVIEW, 1954, 94 (03) :630-638
[3]   FACTORS INFLUENCING CONTRAST IN FAST SPIN-ECHO MR IMAGING [J].
CONSTABLE, RT ;
ANDERSON, AW ;
ZHONG, J ;
GORE, JC .
MAGNETIC RESONANCE IMAGING, 1992, 10 (04) :497-511
[4]  
DU YP, 1996, JMRI-J MAGN RESON IM, V1, P99
[5]   ABSOLUTE QUANTITATION OF WATER AND METABOLITES IN THE HUMAN BRAIN .1. COMPARTMENTS AND WATER [J].
ERNST, T ;
KREIS, R ;
ROSS, BD .
JOURNAL OF MAGNETIC RESONANCE SERIES B, 1993, 102 (01) :1-8
[6]   A MAGNETIZATION-TRANSFER IMAGING STUDY OF NORMAL-APPEARING WHITE-MATTER IN MULTIPLE-SCLEROSIS [J].
FILIPPI, M ;
CAMPI, A ;
DOUSSET, V ;
BARATTI, C ;
MARTINELLI, V ;
CANAL, N ;
SCOTTI, G ;
COMI, G .
NEUROLOGY, 1995, 45 (03) :478-482
[7]   Cerebral white matter: Technical development and clinical applications of effective magnetization transfer (MT) power concepts for high-power, thin-section, quantitative MT examinations [J].
Finelli, DA ;
Hurst, GC ;
Amantia, P ;
Gullapali, RP ;
Apicella, A .
RADIOLOGY, 1996, 199 (01) :219-226
[8]  
FULLERTON GD, 1992, MAGNETIC RESONANCE I
[9]  
Furst G, 1996, AM J NEURORADIOL, V17, P1749
[10]   A quantitative study of ramped radio frequency, magnetization transfer, and slab thickness in three-dimensional time-of-flight magnetic resonance angiography in a patient population [J].
Goodrich, KC ;
Blatter, DD ;
Parker, DL ;
Du, YPP ;
Meyer, KJ ;
Bernstein, MA .
INVESTIGATIVE RADIOLOGY, 1996, 31 (06) :323-332