Psychobiological responses to social threat: Evolution of a psychological model in psychoneuroimmunology

被引:86
作者
Kemeny, Margaret E. [1 ]
机构
[1] Univ Calif San Francisco, Sch Med, Dept Psychiat, Hlth Psychol Program, San Francisco, CA 94143 USA
关键词
Social status; Stress; HPA axis; Inflammation; Cytokines; Cognition; Psychology; AIDS-RELATED BEREAVEMENT; IMMUNE-SYSTEM; GAY MEN; GLUCOCORTICOID-RESISTANCE; NEUROENDOCRINE REGULATION; PSYCHOSOCIAL STRESS; CORTISOL RESPONSES; HIV PROGRESSION; SHAME; BEHAVIOR;
D O I
10.1016/j.bbi.2008.08.008
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
There exists a bidirectional network of interactions between the central nervous system, the endocrine system and the immune system.-The existence of these pathways allows stressful life experience to impact the immune system with important implications for health. One powerful elicitor of changes in the autonomic, endocrine and immune systems is threat to social status. This review describes the development of a human model of social status threat that specifies a set of contextual, psychological and biological pathways that may underlie the health consequences of threats to social status and regard. The role of cognitive processes in shaping the physiological response to the social world will be emphasized. (c) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:1 / 9
页数:9
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