Hepatitis B virus infection: Understanding its epidemiology, course, and diagnosis

被引:61
作者
Elgolihari, Hesham M. [2 ,3 ]
Tamimi, Tareki I. Abu-Rajab [1 ]
Carey, William D. [1 ]
机构
[1] Cleveland Clin, Dept Gastroenterol & Hepatol, Cleveland, OH 44195 USA
[2] Univ S Dakota, Sch Med, Sioux Falls, SD USA
[3] Transplant Inst, Avera Ctr Liver Dis, Sioux Falls, SD USA
关键词
D O I
10.3949/ccjm.75a.07019
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Although hepatitis B virus (HBV) infection is not as common in the United States as in some countries, 5,000 Americans die from it every year. This number can be significantly decreased with proper screening and by vaccinating people at risk. Internists should be aware of the natural history of HBV infection, a vital prerequisite to correctly assessing disease severity and subsequently determining the need for antiviral therapy.
引用
收藏
页码:881 / 889
页数:9
相关论文
共 38 条
[1]   Identification and characterization of mutations in hepatitis B virus resistant to lamivudine [J].
Allen, MI ;
Deslauriers, M ;
Andrews, CW ;
Tipples, GA ;
Walters, KA ;
Tyrrell, DLJ ;
Brown, N ;
Condreay, LD .
HEPATOLOGY, 1998, 27 (06) :1670-1677
[2]   Childhood hepatitis B virus infections in the United States before hepatitis B immunization [J].
Armstrong, GL ;
Mast, EE ;
Wojczynski, M ;
Margolis, HS .
PEDIATRICS, 2001, 108 (05) :1123-1128
[3]   Natural history of compensated viral cirrhosis:: a prospective study on the incidence and hierarchy of major complications [J].
Benvegnù, L ;
Gios, M ;
Boccato, S ;
Alberti, A .
GUT, 2004, 53 (05) :744-749
[4]   Chronic hepatitis B in children after e antigen seroclearance: Final report of a 29-year longitudinal study [J].
Bortolotti, F ;
Guido, M ;
Bartolacci, S ;
Cadrobbi, P ;
Crivellaro, C ;
Noventa, F ;
Morsica, G ;
Moriondo, M ;
Gatta, A .
HEPATOLOGY, 2006, 43 (03) :556-562
[5]   Hepatitis B virus genotypes and extrahepatic manifestations [J].
Cacoub, P ;
Saadoun, D ;
Bourlière, M ;
Khiri, H ;
Martineau, A ;
Benhamou, Y ;
Varastet, M ;
Pol, S ;
Thibault, V ;
Rotily, M ;
Halfon, P .
JOURNAL OF HEPATOLOGY, 2005, 43 (05) :764-770
[6]  
*CDCP, HBV SIL KILL
[7]   Hepatitis B virus genotypes in the United States: Results of a nationwide study [J].
Chu, CJ ;
Keeffe, EB ;
Han, SH ;
Perrillo, RP ;
Min, AD ;
Soldevila-Pico, C ;
Carey, W ;
Brown, RS ;
Luketic, VA ;
Terrault, N ;
Lok, ASF .
GASTROENTEROLOGY, 2003, 125 (02) :444-451
[8]   THE ETIOLOGY OF ACUTE HEPATITIS SUPERIMPOSED UPON PREVIOUSLY UNRECOGNIZED ASYMPTOMATIC HBSAG-CARRIERS [J].
CHU, CM ;
LIAW, YF ;
PAO, CC ;
HUANG, MJ .
HEPATOLOGY, 1989, 9 (03) :452-456
[9]   REGIONAL PREVALENCE OF HEPATITIS-B, HEPATITIS-DELTA, AND HUMAN IMMUNODEFICIENCY VIRUS-INFECTION IN SOUTHERN-AFRICA - A LARGE POPULATION SURVEY [J].
DUSHEIKO, GM ;
BRINK, BA ;
CONRADIE, JD ;
MARIMUTHU, T ;
SHER, R .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1989, 129 (01) :138-145
[10]  
Fattovich Giovanna, 2003, Journal of Hepatology, V39, pS50