The structure and ligand interactions of CD2: Implications for T-cell function

被引：351
作者：
Davis, SJ [1 ]
vanderMerwe, PA [1 ]
机构：
[1] UNIV OXFORD,SIR WILLIAM DUNN SCH PATHOL,MRC,CELLULAR IMMUNOL UNIT,OXFORD OX1 3RE,ENGLAND
来源：
IMMUNOLOGY TODAY | 1996年 / 17卷 / 04期
基金：
英国惠康基金;
关键词：
D O I：
10.1016/0167-5699(96)80617-7
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Considerable progress has recently been made in understanding the structure and ligand interactions of the T-cell antigen CD2, to the extent that CD2 is now a useful paradigm for considering the structural basis of cell-cell recognition. Here, Simon Davis and Anton van der Merwe review the new data and consider their implications and T-cell function in the context of CD2-knockout experiments.
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页码：177 / 187
页数：11
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