COVID-19 and the endothelium

被引：71

作者：

Jung, F. ^{[1
]}

Krueger-Genge, A. ^{[2
]}

Franke, R. P. ^{[3
]}

Hufert, F. ^{[4
,5
]}

Kuepper, J. -H. ^{[1
,5
]}

机构：

[1] Brandenburg Univ Technol Cottbus Senftenberg, Mol Cell Biol, Inst Biotechnol, Cottbus, Germany

[2] Fraunhofer Inst Appl Polymer Res IAP, Div Life Sci & Bioproc, Dept Healthcare Biomat & Cosmeceut, Potsdam, Germany

[3] Univ Ulm, Dept Biomat, Ulm, Germany

[4] Brandenburg Med Sch Fontane, Inst Microbiol & Virol, Senftenberg, Germany

[5] Brandenburg Med Sch Fontane & Univ Potsdam, Joint Fac Brandenburg Univ Technol Cottbus Senfte, Fac Hlth Sci, Potsdam, Germany

来源：

CLINICAL HEMORHEOLOGY AND MICROCIRCULATION | 2020年 / 75卷 / 01期

关键词：

COVID-19; endocytosis; endothelial cell dysfunction; endotheliitis; PULMONARY-EMBOLISM; ACE2; SARS-COV-2; RECEPTOR; CORONAVIRUS; EXPRESSION; CELLS;

D O I：

10.3233/CH-209007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There is growing evidence that COVID-19 not only affects the lungs but beyond that the endothelial system. Recent studies showed that this can lead to microcirculatory impairments and in consequence to functional disorders of all inner organs. The combination of endothelial dysfunction with a generalized inflammatory state and complement elements may together contribute to the overall pro-coagulative state described in COVID-19 patients leading to venular as well as to arteriolar occlusions.

引用

页码：7 / 11

页数：5

共 50 条

[1] The Enigma of Endothelium in COVID-19
Kaur, Savneet
Tripathi, Dinesh M.
Yadav, Angeera
FRONTIERS IN PHYSIOLOGY, 2020, 11
[2] Targeting the Vascular Endothelium in the Treatment of COVID-19
Suvorava, Tatsiana
Kaesemeyer, Wayne
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2021, 77 (01) : 1 - 3
[3] The Role of Endothelium in COVID-19
Ionescu, Mihaela
Stoian, Anca Pantea
Rizzo, Manfredi
Serban, Dragos
Nuzzo, Domenico
Mazilu, Laura
Suceveanu, Andra Iulia
Dascalu, Ana Maria
Parepa, Irinel Raluca
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (21)
[4] The role of platelets, neutrophils and endothelium in COVID-19 infection
Falcinelli, E.
Petito, E.
Gresele, P.
EXPERT REVIEW OF HEMATOLOGY, 2022, 15 (08) : 727 - 745
[5] A review of pathophysiology and neuropsychiatric manifestations of COVID-19
Jasti, Madhu
Nalleballe, Krishna
Dandu, Vasuki
Onteddu, Sanjeeva
JOURNAL OF NEUROLOGY, 2021, 268 (06) : 2007 - 2012
[6] The implications of COVID-19 infection on the endothelium: A metabolic vascular perspective
Dalan, Rinkoo
Boehm, Bernhard O.
DIABETES-METABOLISM RESEARCH AND REVIEWS, 2021, 37 (03)
[7] The endothelium as Achilles' heel in COVID-19 patients
Gladka, Monika M.
Maack, Christoph
CARDIOVASCULAR RESEARCH, 2020, 116 (14) : E195 - E197
[8] Hematological changes in patients with COVID-19
Ye, Jieyu
Jiao, Yingying
Zhang, Yujiao
Li, Zongpeng
Zeng, Xiaoyuan
Deng, Huixia
Yang, Mo
MOLECULAR MEDICINE REPORTS, 2020, 22 (06) : 4485 - 4491
[9] Metainflammation in COVID-19
Bakhtiari, Mojtaba
Asadipooya, Kamyar
ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2022, 22 (12) : 1154 - 1166
[10] Pathophysiology of COVID-19
Manta, Bruno
Sarkisian, Armen G.
Garcia-Fontana, Barbara
Pereira-Prado, Vanesa
ODONTOESTOMATOLOGIA, 2022, 24 (39):

← 1 2 3 4 5 →