NK/T-cell lymphoma of bilateral adrenal glands in a patient with pyothorax

被引：12

作者：

Tsukahara, Tomohide ^{[1
]}

Takasawa, Akira ^{[1
]}

Murata, Masaki ^{[1
]}

Okumura, Kazuyoshi ^{[2
]}

Nakayama, Masato ^{[2
]}

Sato, Noriyuki ^{[1
]}

Hasegawa, Tadashi ^{[3
]}

机构：

[1] Sapporo Med Univ, Dept Pathol, Chou Ku, Sapporo, Hokkaido 0608556, Japan

[2] Tenshi Hosp, Dept Surg, Higashi Ku, Sapporo, Hokkaido 0650012, Japan

[3] Sapporo Med Univ Hosp, Div Clin Pathol, Chuo Ku, Sapporo, Hokkaido 0608543, Japan

来源：

DIAGNOSTIC PATHOLOGY | 2012年 / 7卷

关键词：

NK/T-cell lymphoma; Adrenal gland; EBV; Pyothorax; Autopsy;

D O I：

10.1186/1746-1596-7-114

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Primary lymphoma of adrenal glands is rare, and non-B-cell lymphoma associated with pyothorax is also very rare. Here we report the first autopsy case of non-B-cell lymphoma in bilateral adrenal glands of a 79-year-old woman with pyothorax who had an aggressive clinical course. Immunohistochemically, tumor cells showed CD3+, CD45RO+, CD5-, CD7-, CD4-, CD8-, CD10-, CD20-, CD30-, CD79a-, CD138-, CD56-, granzyme B-, TIA-1+ and ALK-. In addition, tumor cells were strongly EBER1-positive by in situ hybridization. In genomic DNA of tumor cells, T-cell receptor rearrangements were not detected by southern blotting. We finally diagnosed this case as extranodal NK/T-cell lymphoma (nasal type).

引用

页数：5

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