Drug Utilization Evaluation of Anticancer Drugs in a Charitable Hospital

被引:4
作者
Mathew, Maneesha [1 ]
Mateti, Uday Venkat [1 ]
Saj, Neethu [1 ]
Philip, Malona Lilly [1 ]
Shetty, Vijith [2 ]
机构
[1] Nitte, Dept Pharm Practice, NGSM Inst Pharmaceut Sci, Mangaluru, Karnataka, India
[2] Nitte, Dept Med Oncol, KS Hegde Med Acad, Justice KS Hegde Charitable Hosp, Mangaluru 575018, Karnataka, India
关键词
Cancer; chemotherapy; prescribing patterns; World Health Organization;
D O I
10.4103/ijmpo.ijmpo_156_18
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Evaluating the prescribing patterns of anticancer and supportive care drugs is necessary for ensuring effectiveness and patient's quality of life. Aim: This study aims to evaluate the prescribing patterns in patients receiving chemotherapy. Settings and Design: A prospective observational study was conducted in the Department of Medical Oncology at Justice K. S. Hegde Charitable Hospital. Methods: The study was conducted for 8 months from September 2017 to April 2018. Cancer patients who were above 18 years and are on chemotherapy along with supportive cam medications were enrolled. Statistical Analysis: Data were analyzed using descriptive statistics. Continuous data were expressed as meant +/- standard deviation, and the nominal data were expressed as frequency and percentages. Results: Among 230 patients, majority of patients were in the age group of 45-60 years (47%), females (51.7%), Stage III (51.3%), solid tumor (85.5%), breast cancer (21.7%), doublet regimen (60.4%), who received doxorubicin and cyclophosphamide (36%) in breast cancer while paclitaxel and carboplatin (16.52%) were mostly prescribed among the different cancer types. The most commonly prescribed supportive care medications were dexamethasone (100%), ranitidine (100%), filgmstim (67.4%), tramadol and paracetamol (23.91%), and levofloxacin (9.56%). The percentage of drugs prescribed from the National List Essential Medicine and the World Health Organization (WHO) model list was 80.84% and 78.92%, respectively. Conclusion: According to the WHO core prescribing indicators, the average number of drugs per prescription was 9.63. Majority of the cancer patients were prescribed with paclitaxel and carboplatin (16.52%); dexamethasone and ranitidine (100%) were coadministered in all patients during their chemotherapy cycles.
引用
收藏
页码:105 / 110
页数:6
相关论文
共 13 条
[1]  
[Anonymous], 1999, Informal Consultation on Monitoring of Drug Efficacy in the Control of Schistosomiasis and Intestinal Nematodes, P1
[2]  
[Anonymous], 2017, WHO MODEL LIST ESSEN
[3]  
[Anonymous], 1993, World Health Organization, V1, P1
[4]  
[Anonymous], 2015, National List of Essential Medicines
[5]  
Catic Tarik, 2016, Mater Sociomed, V28, P112, DOI 10.5455/msm.2016.28.112-114
[6]  
Longo DL., 2015, HARRISONS PRINCIPLES, P467
[7]  
Manichavasagam M, 2017, ANN MED HEALTH SCI R, V7, P1
[8]  
Mugada V, 2016, J APPL PHARM SCI, V6, P98, DOI DOI 10.7324/JAPS.2016.601013
[9]  
Onwusah DO, 2017, SCH ACAD J PHARM, V6, P158
[10]  
Pentareddy MR, 2015, J Evid Based Med Healthc, V2, P3001