H2S to Mitigate Vascular Aging: A SIRT1 Connection

被引：23

作者：

Arumugam, Thiruma V. ^{[1
,2
]}

Kennedy, Brian K. ^{[1
,3
,4
]}

机构：

[1] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Physiol, MD9,2 Med Dr, Singapore 117593, Singapore

[2] Sungkyunkwan Univ, Sch Pharm, Suwon 16419, South Korea

[3] Yong Loo Lin Sch Med, Dept Biochem, MD7,8 Med Dr, Singapore 117596, Singapore

[4] Buck Inst Res Aging, Novato, CA 94945 USA

来源：

CELL | 2018年 / 173卷 / 01期

关键词：

HYDROGEN-SULFIDE; GROWTH;

D O I：

10.1016/j.cell.2018.03.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

H2S is an endogenous gasotransmitter that plays an important role in physiological conditions. In this issue, Das et al. provide evidence that SIRT1-dependent angiogenesis is augmented by H2S-findings reinforced by Longchamp et al., who demonstrate that H2S-dependent angiogenesis is triggered by amino acid deprivation.

引用

页码：8 / 10

页数：3

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