Synthesis and Antibacterial Activity of 5-Aryl-4-[hydroxy(4-chlorophenyl)methylene]-1-[2-(1H-indol-3-yl)ethyl]pyrrolidine-2,3-diones

被引：4

作者：

Gein, V. L. ^{[1
]}

Kazantseva, M. I. ^{[2
]}

Varkentin, L. I. ^{[1
]}

Zamaraeva, T. M. ^{[1
]}

Yankin, A. N. ^{[3
]}

Beletskii, E. V. ^{[4
]}

Novikova, V. V. ^{[1
]}

机构：

[1] Perm State Pharmaceut Acad, Perm 614990, Russia

[2] EA Vagner Perm State Med Univ, Perm 614990, Russia

[3] ITMO Univ, St Petersburg 197101, Russia

[4] St Petersburg State Univ, St Petersburg 199034, Russia

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2020年 / 90卷 / 08期

关键词：

N; N-dimethyltryptamine heterocyclic analogues; pyrrolidine-2; 3-dione derivatives; antimicrobial activity; INHIBITORY-ACTIVITY; DERIVATIVES; EFFICIENT;

D O I：

10.1134/S1070363220080083

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of tryptamine with aromatic aldehydes and 4-chlorobenzoylpyruvic acid methyl ester led to the formation of 5-aryl-4-[hydroxy-(4-chlorophenyl)methylene]-1-[2-(1H-indol-3-yl)ethyl]pyrrolidine-2,3-diones. The resulting compounds were tested for antimicrobial activity.

引用

页码：1426 / 1431

页数：6

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