Osteosarcoma of the jaw: an analysis of a series of 74 cases

被引：44

作者：

Luisa Paparella, Maria ^{[1
,2
]}

Graciela Olvi, Liliana ^{[2
]}

Brandizzi, Daniel ^{[3
,4
]}

Keszler, Alicia ^{[1
]}

Santini-Araujo, Eduardo ^{[1
,2
]}

Luis Cabrini, Romulo ^{[1
,3
,4
]}

机构：

[1] Univ Buenos Aires, Sch Dent, Dept Oral Pathol, Buenos Aires, DF, Argentina

[2] Lab Orthopaed Pathol, Buenos Aires, DF, Argentina

[3] Natl Atom Energy Commiss Constituyentes Atom Ctr, Dept Radiobiol, Radiat Pathol Div, Buenos Aires, DF, Argentina

[4] CNR, CONICET, CNEA, Natl Lab Res & Serv Microspectrophotometry LANAIS, Buenos Aires, DF, Argentina

来源：

HISTOPATHOLOGY | 2013年 / 63卷 / 04期

关键词：

jaw; osteosarcoma; sarcoma; OSTEOGENIC-SARCOMA; EXPRESSION; BONES; HEAD; EXPERIENCE; NECK;

D O I：

10.1111/his.12191

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

AimsTo analyse a series of cases of osteosarcoma of the jaw. Methods and resultsThe study included 74 cases of osteosarcoma of the jaw. Their clinical, radiographic and histopathological features were analysed, and their frequency with respect to aggressive and malignant pathologies of the jaw was determined. Survival was assessed in 17 cases with available follow-up. Osteosarcoma of the jaw accounted for 10% of primary malignant and aggressive tumours of the jaw, and for 8% of all malignant lesions of the jaw, including metastatic and lymphoproliferative tumours. The mean age was 4318years. Radiographic features varied greatly and were non-specific, with a predominance of mixed images. The dominant histological pattern was osteoblastic (48.4%), followed by chondroblastic (37.1%). The survival rate at 5years was 68%. Females and patients with a predominantly chondroblastic pattern had lower survival rates. ConclusionsOsteosarcoma of the jaw was the most frequent primary malignant tumour of the jaw. Female gender and a predominantly chondroblastic pattern may be associated with a worse prognosis.

引用

页码：551 / 557

页数：7

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