Stem cell fate regulation by dynein motor protein Lis1

被引：5
作者：
Will, Britta [1 ,2 ]
Steidl, Ulrich [3 ,4 ]
机构：
[1] Albert Einstein Coll Med, Dept Cell Biol, New York, NY 10461 USA
[2] Albert Einstein Coll Med, Ruth L & David S Gottesman Inst Stem Cell & Regen, New York, NY USA
[3] Albert Einstein Coll Med, Montefiore Med Ctr, Dept Cell Biol,Dept Med Oncol, Ruth L & David S Gottesman Inst Stem Cell & Regen, New York, NY USA
[4] Albert Einstein Coll Med, Montefiore Med Ctr, Albert Einstein Canc Ctr, New York, NY USA
来源：
NATURE GENETICS | 2014年 / 46卷 / 03期
关键词：
DIVISION; QUIESCENCE;
D O I：
10.1038/ng.2902
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Cell fate regulation is a central component of maintaining tissue homeostasis, yet the mechanisms instructing cell division diversity in tissue-specific stem cells have not been well understood. A new study uncovers a central role for microtubule motor-regulating protein Lis1 in hematopoietic stem cell fate determination and in leukemogenesis.
引用
收藏
页码：217 / 218
页数：3
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