Congenital Cytomegalovirus Infection: Clinical Outcome

被引：264
作者：
Boppana, Suresh B. [1 ,2 ]
Ross, Shannon A. [1 ,2 ]
Fowler, Karen B. [1 ,3 ,4 ]
机构：
[1] Univ Alabama Birmingham, Dept Pediat, Birmingham, AL USA
[2] Univ Alabama Birmingham, Dept Microbiol, Birmingham, AL 35294 USA
[3] Univ Alabama Birmingham, Dept Epidemiol, Birmingham, AL USA
[4] Univ Alabama Birmingham, Dept Maternal & Child Hlth, Birmingham, AL USA
来源：
CLINICAL INFECTIOUS DISEASES | 2013年 / 57卷
关键词：
cytomegalovirus; congenital; outcome; sensorineural hearing loss; HEARING-LOSS; PREEXISTING IMMUNITY; PRENATAL-DIAGNOSIS; CHILDREN; POPULATION; PREVALENCE; MORTALITY; NEWBORNS; SEQUELAE; INFANTS;
D O I：
10.1093/cid/cit629
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Congenital cytomegalovirus (CMV) infection is a leading cause of hearing loss and neurologic disabilities in children worldwide. Infants with symptomatic congenital CMV infection at birth are at significantly increased risk for developing adverse long-term outcomes. The vast majority of infants with congenital CMV infection have no clinical findings at birth (asymptomatic infants), and about 10%-15% of these children develop long-term sequelae. Currently, predictors of adverse outcome in asymptomatic congenital CMV infection are not known, and it is important that future studies address this issue.
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收藏
页码：S178 / S181
页数：4
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