Critical overview on the application of sensors and biosensors for clinical analysis

被引：109

作者：

Justino, Celine I. L. ^{[1
,2
,3
]}

Duarte, Armando C. ^{[1
,2
]}

Rocha-Santos, Teresa A. P. ^{[1
,2
]}

机构：

[1] Univ Aveiro, Dept Chem, Campus Santiago, P-3810193 Aveiro, Portugal

[2] Univ Aveiro, CESAM, Campus Santiago, P-3810193 Aveiro, Portugal

[3] Inst Piaget, ISEIT Viseu, Estr Alto Gaio, P-3515776 Lordosa, Viseu, Portugal

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2016年 / 85卷

关键词：

Analytical performance; Biosensor; Clinical analysis; Figure of merit; Sensor; C-REACTIVE PROTEIN; NONENZYMATIC GLUCOSE SENSOR; SURFACE-PLASMON RESONANCE; SIGNAL AMPLIFICATION STRATEGY; LABEL-FREE DETECTION; ELECTROCHEMICAL IMMUNOSENSOR; GOLD NANOPARTICLES; CARBON NANOTUBES; GRAPHENE OXIDE; CARCINOEMBRYONIC ANTIGEN;

D O I：

10.1016/j.trac.2016.04.004

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Sensors and biosensors have been increasingly used for clinical analysis due to their miniaturization and portability, allowing the construction of diagnostic devices for point-of-care testing. This paper presents an up-to-date overview and comparison of the analytical performance of sensors and biosensors recently used in clinical analysis. This includes cancer and cardiac biomarkers, hormones, biomolecules, neurotransmitters, bacteria, virus and cancer cells, along with related significant advances since 2011. Some methods of enhancing the analytical performance of sensors and biosensors through their figures of merit are also discussed. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：36 / 60

页数：25

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