CNS inflammatory vasculopathy with antimyelin oligodendrocyte glycoprotein antibodies in COVID-19

被引：45

作者：

Pinto, Ashwin A. ^{[1
,2
]}

Carroll, Liam S. ^{[1
]}

Nar, Vijay ^{[1
]}

Varatharaj, Aravinthan ^{[1
,2
]}

Galea, Ian ^{[1
,2
]}

机构：

[1] Southampton Gen Hosp, Wessex Neurol Ctr, Southampton, Hants, England

[2] Univ Southampton, Fac Med, Clin & Expt Sci, Clin Neurosci, Southampton SO9 5NH, Hants, England

来源：

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION | 2020年 / 7卷 / 05期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1212/NXI.0000000000000813

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 44-year-old right-handed woman reported a gradual onset of right hand incoordination seven days after the onset of minor respiratory symptoms and pruritus due to COVID-19 infection. Over 48 hours, the patient developed word-finding difficulties and progression in right arm weakness leading to presentation to the emergency department as a suspected stroke.

引用

页数：3

共 7 条

[1] What is the blood-brain barrier (not)? [J].

Bechmann, Ingo ;

Galea, Ian ;

Perry, V. Hugh .

TRENDS IN IMMUNOLOGY, 2007, 28 (01) :5-11

[2] MRI features of demyelinating disease associated with anti-MOG antibodies in adults [J].

Deneve, Marc ;

Biotti, Damien ;

Patsoura, Sofia ;

Ferrier, Marine ;

Meluchova, Zuzana ;

Mahieu, Laurence ;

Heran, Francoise ;

Vignal, Catherine ;

Deschamps, Romain ;

Gout, Olivier ;

de Champfleur, Nicolas Menjot ;

Ayrignac, Xavier ;

Dalliere, Clarisse Carra ;

Labauge, Pierre ;

Dulau, Cecile ;

Tourdias, Thomas ;

Dumas, Herve ;

Cognard, Christophe ;

Brassat, David ;

Bonneville, Fabrice .

JOURNAL OF NEURORADIOLOGY, 2019, 46 (05) :312-318

[3] Clinical presentation and prognosis in MOG-antibody disease: a UK study [J].

Jurynczyk, Maciej ;

Messina, Silvia ;

Woodhall, Mark R. ;

Raza, Naheed ;

Everett, Rosie ;

Roca-Fernandez, Adriana ;

Tackley, George ;

Hamid, Shahd ;

Sheard, Angela ;

Reynolds, Gavin ;

Chandratre, Saleel ;

Hemingway, Cheryl ;

Jacob, Anu ;

Vincent, Angela ;

Leite, M. Isabel ;

Waters, Patrick ;

Palace, Jacqueline .

BRAIN, 2017, 140 :3128-3138

[4] Perivascular enhancement in anti-MOG antibody demyelinating disease of the CNS [J].

Komatsu, Teppei ;

Matsushima, Satoshi ;

Kaneko, Kimihiko ;

Fukuda, Takahiro .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2019, 90 (01) :111-112

[5] Endothelial cell infection and endotheliitis in COVID-19 [J].

Varga, Zsuzsanna ;

Flammer, Andreas J. ;

Steiger, Peter ;

Haberecker, Martina ;

Andermatt, Rea ;

Zinkernagel, Annelies S. ;

Mehra, Mandeep R. ;

Schuepbach, Reto A. ;

Ruschitzka, Frank ;

Moch, Holger .

LANCET, 2020, 395 (10234) :1417-1418

[6] Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2 [J].

Vonck, K. ;

Garrez, I. ;

De Herdt, V. ;

Hemelsoet, D. ;

Laureys, G. ;

Raedt, R. ;

Boon, P. .

EUROPEAN JOURNAL OF NEUROLOGY, 2020, 27 (08) :1578-1587

[7] Angiotensin-converting enzyme 2 in the brain: properties and future directions [J].

Xia, Huijing ;

Lazartigues, Eric .

JOURNAL OF NEUROCHEMISTRY, 2008, 107 (06) :1482-1494

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