Late-life depression: issues for the general practitioner

被引:24
作者
Van Damme, Axel [1 ]
Declercq, Tom [2 ]
Lemey, Lieve [3 ]
Tandt, Hannelore [4 ]
Petrovic, Mirko [5 ]
机构
[1] Univ Ghent, Fac Med & Hlth Sci, Ghent, Belgium
[2] Univ Ghent, Dept Gen Practice & Primary Hlth Care, Ghent, Belgium
[3] AZ Sint Jan Brugge Oostende AV, Dept Psychiat, Brugge, Belgium
[4] Ghent Univ Hosp, Dept Psychiat, Ghent, Belgium
[5] Univ Ghent, Dept Internal Med, Sect Geriatr, Heymanslaan 10, B-9000 Ghent, Belgium
来源
INTERNATIONAL JOURNAL OF GENERAL MEDICINE | 2018年 / 11卷
关键词
geriatric mental health; major depressive disorder; elder care; psychosomatic; geriatric psychiatry; SEROTONIN REUPTAKE INHIBITORS; OLDER-ADULTS; RISK-FACTORS; ELECTROCONVULSIVE-THERAPY; PRIMARY-CARE; COLLABORATIVE CARE; METAANALYSIS; DISEASE; PREVALENCE; EFFICACY;
D O I
10.2147/IJGM.S154876
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Late-life depression (LLD) is both a prevalent and life-threatening disorder, affecting up to 13.3% of the elderly population. LLD can be difficult to identify because patients mainly consult their general practitioner (GP) for somatic complaints. Moreover, patients may be hesitant to express the problem to their GP. Increased vigilance on the part of the GP can only benefit older people with depression. To recognize the risk of LLD, screening tools are provided in addition to treatment options for LLD. This review aims to provide the GP with guidance in recognizing and treating LLD. It tries to connect mainstream etiologies of LLD (e.g., vascular, inflammation, hypothalamo-pituitary-adrenal axis) with risk factors and current therapies. Therefore, we provide a basis to the GP for decision-making when choosing an appropriate therapy for LLD.
引用
收藏
页码:113 / 120
页数:8
相关论文
共 87 条
[41]   A Systematic Review and Meta-analysis of Psychotherapy for Late-Life Depression [J].
Huang, Alice X. ;
Delucchi, Kevin ;
Dunn, Laura B. ;
Nelson, J. Craig .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2015, 23 (03) :261-273
[42]   Cardiovascular risk factors may moderate pharmacological treatment effects in major depressive disorder [J].
Iosifescu, DV ;
Clementi-Craven, N ;
Fraguas, R ;
Papakostas, GI ;
Petersen, T ;
Alpert, JE ;
Nierenberg, AA ;
Fava, M .
PSYCHOSOMATIC MEDICINE, 2005, 67 (05) :703-706
[43]   Hyponatremia associated with selective serotonin reuptake inhibitors, mirtazapine and venlafaxine, in Korean patients with major depressive disorder [J].
Jung, Y. -E. ;
Jun, T. -Y. ;
Kim, K. -S. ;
Bahk, W. -M. .
INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2011, 49 (07) :437-443
[44]   Relationship between late-life depression and life stressors: Large-scale cross-sectional study of a representative sample of the Japanese general population [J].
Kaji, Tatsuhiko ;
Mishima, Kazuo ;
Kitamura, Shingo ;
Enomoto, Minori ;
Nagase, Yukihiro ;
Li, Lan ;
Kaneita, Yoshitaka ;
Ohida, Takashi ;
Nishikawa, Toru ;
Uchiyama, Makoto .
PSYCHIATRY AND CLINICAL NEUROSCIENCES, 2010, 64 (04) :426-434
[45]   Cerebrovascular disease and late-life depression [J].
Kales, HC ;
Maixner, DF ;
Mellow, AM .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2005, 13 (02) :88-98
[46]   Falls, Depression and Antidepressants in Later Life: A Large Primary Care Appraisal [J].
Kerse, Ngaire ;
Flicker, Leon ;
Pfaff, Jon J. ;
Draper, Brian ;
Lautenschlager, Nicola T. ;
Sim, Moira ;
Snowdon, John ;
Almeida, Osvaldo P. .
PLOS ONE, 2008, 3 (06)
[47]   Efficacy of treatment in older depressed patients: A systematic review and meta-analysis of double-blind randomized controlled trials with antidepressants [J].
Kok, Rob M. ;
Nolen, Willem A. ;
Heeren, Thea J. .
JOURNAL OF AFFECTIVE DISORDERS, 2012, 141 (2-3) :103-115
[48]   Depression and dementia [J].
Korczyn, Amos D. ;
Halperin, Ilan .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2009, 283 (1-2) :139-142
[49]   Life review therapy for older adults with moderate depressive symptomatology: a pragmatic randomized controlled trial [J].
Korte, J. ;
Bohlmeijer, E. T. ;
Cappeliez, P. ;
Smit, F. ;
Westerhof, G. J. .
PSYCHOLOGICAL MEDICINE, 2012, 42 (06) :1163-1173
[50]   Systematic Review of Cognitive Effects of Electroconvulsive Therapy in Late-Life Depression [J].
Kumar, Sanjeev ;
Mulsant, Benoit H. ;
Liu, Angela Y. ;
Blumberger, Daniel M. ;
Daskalakis, Zafiris J. ;
Rajji, Tarek K. .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2016, 24 (07) :547-565