General overview of blood products in vitro quality: Processing and storage lesions

被引:10
作者
Abonnenc, Melanie [1 ]
Tissot, Jean-Daniel [1 ,2 ]
Prudent, Michel [1 ,2 ]
机构
[1] Transfus Interreg CRS, Lab Rech Prod Sanguins, Route Corniche 2, CH-1066 Epalinges, Switzerland
[2] Univ Lausanne, Fac Biol & Med, Lausanne, Switzerland
关键词
Plasma; Platelet; Processing; Red blood cell; Storage; Transfusion; PATHOGEN-REDUCTION TECHNOLOGY; FRESH-FROZEN PLASMA; BUFFY COAT PLATELETS; CELL STORAGE; FUNCTIONAL-CHARACTERISTICS; PHOTOCHEMICAL TREATMENT; ULTRAVIOLET-LIGHT; ADDITIVE SOLUTION; METHYLENE-BLUE; PROTEIN CARBONYLATION;
D O I
10.1016/j.tracli.2018.08.162
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Blood products are issued from blood collection. Collected blood is immediately mixed with anticoagulant solutions that immediately induce chemical and/or biochemical modifications. Collected blood is then transformed into different blood products according to various steps of fabrication. All these steps induce either reversible or irreversible "preparation-related" lesions that combine with "storage-related" lesions. This short paper aims to provide an overview of the alterations that are induced by the "non-physiological" processes used to prepare blood products that are used in clinical practice. (C) 2018 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:269 / 275
页数:7
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