General overview of blood products in vitro quality: Processing and storage lesions

被引：10

作者：

Abonnenc, Melanie ^{[1
]}

Tissot, Jean-Daniel ^{[1
,2
]}

Prudent, Michel ^{[1
,2
]}

机构：

[1] Transfus Interreg CRS, Lab Rech Prod Sanguins, Route Corniche 2, CH-1066 Epalinges, Switzerland

[2] Univ Lausanne, Fac Biol & Med, Lausanne, Switzerland

来源：

TRANSFUSION CLINIQUE ET BIOLOGIQUE | 2018年 / 25卷 / 04期

关键词：

Plasma; Platelet; Processing; Red blood cell; Storage; Transfusion; PATHOGEN-REDUCTION TECHNOLOGY; FRESH-FROZEN PLASMA; BUFFY COAT PLATELETS; CELL STORAGE; FUNCTIONAL-CHARACTERISTICS; PHOTOCHEMICAL TREATMENT; ULTRAVIOLET-LIGHT; ADDITIVE SOLUTION; METHYLENE-BLUE; PROTEIN CARBONYLATION;

D O I：

10.1016/j.tracli.2018.08.162

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Blood products are issued from blood collection. Collected blood is immediately mixed with anticoagulant solutions that immediately induce chemical and/or biochemical modifications. Collected blood is then transformed into different blood products according to various steps of fabrication. All these steps induce either reversible or irreversible "preparation-related" lesions that combine with "storage-related" lesions. This short paper aims to provide an overview of the alterations that are induced by the "non-physiological" processes used to prepare blood products that are used in clinical practice. (C) 2018 Elsevier Masson SAS. All rights reserved.

引用

页码：269 / 275

页数：7

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