The stress-inducible molecular chaperone GRP78 as potential therapeutic target for coronavirus infection

被引:65
|
作者
Ha, Dat P. [1 ]
Van Krieken, Richard [1 ]
Carlos, Anthony J. [1 ]
Lee, Amy S. [1 ]
机构
[1] Univ Southern Calif, Dept Biochem & Mol Med, USC Norris Comprehens Canc Ctr, Keck Sch Med, 1441 Eastlake Ave,NOR 5308, Los Angeles, CA 90089 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/j.jinf.2020.06.017
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
引用
收藏
页码:478 / 480
页数:3
相关论文
共 50 条
  • [41] Versipelostatin, a novel GRP78/Bip molecular chaperone down-regulator of microbial origin
    Park, HR
    Furihata, K
    Hayakawa, Y
    Shin-ya, K
    TETRAHEDRON LETTERS, 2002, 43 (39) : 6941 - 6945
  • [42] Actinopyrone D, a new downregulator of the molecular chaperone GRP78 from Streptomyces sp.
    Hayakawa, Yoichi
    Saito, Junki
    Izawa, Masumi
    Shin-ya, Kazuo
    JOURNAL OF ANTIBIOTICS, 2014, 67 (12): : 831 - 834
  • [43] Discovery of a Novel Target for the Dysglycemic Chromogranin A Fragment Pancreastatin: Interaction with the Chaperone GRP78 to Influence Metabolism
    Biswas, Nilima
    Friese, Ryan S.
    Gayen, Jiaur R.
    Bandyopadhyay, Gautam
    Mahata, Sushil K.
    O'Connor, Daniel T.
    PLOS ONE, 2014, 9 (01):
  • [44] Expression of the stress regulated chaperone Grp78 in atherosclerotic aortas - implication of endoplasmic reticulum stress in endothelial dysfunction
    Jorgensen, MM
    Falk, E
    Ledet, T
    Simonsen, U
    HYPERTENSION, 2004, 44 (04) : 566 - 566
  • [45] GRP78 as a potential therapeutic target in cancer treatment: an updated review of its role in chemoradiotherapy resistance of cancer cells
    Lin, Min
    Mo, Yan
    Li, Cheng-min
    Liu, Ying-zhe
    Feng, Xue-ping
    MEDICAL ONCOLOGY, 2025, 42 (02)
  • [46] Allosteric Landscape of a Stress-inducible Human Hsp70 Molecular Chaperone
    Meng, Wenli
    Clerico, Eugenia M.
    McArthur, Natalie
    Gierasch, Lila M.
    FASEB JOURNAL, 2017, 31
  • [47] Dengue Virus Infection Induces Upregulation of GRP78, Which Acts To Chaperone Viral Antigen Production
    Wati, S.
    Soo, M. -L.
    Zilm, P.
    Li, P.
    Paton, A. W.
    Burrell, C. J.
    Beard, M.
    Carr, J. M.
    JOURNAL OF VIROLOGY, 2009, 83 (24) : 12871 - 12880
  • [48] Overexpression of endoplasmic reticulum molecular chaperone GRP94 and GRP78 in human lung cancer tissues and its significance
    Wang, Q
    He, ZZ
    Zhang, JH
    Wang, YY
    Wang, T
    Tong, SP
    Wang, LJ
    Wang, SJ
    Chen, YH
    CANCER DETECTION AND PREVENTION, 2005, 29 (06): : 544 - 551
  • [49] Loss of the Oxidative Stress Sensor NPGPx Compromises GRP78 Chaperone Activity and Induces Systemic Disease
    Wei, Pei-Chi
    Hsieh, Yi-Hsuan
    Su, Mei-I.
    Jiang, Xianzhi
    Hsu, Pang-Hung
    Lo, Wen-Ting
    Weng, Jui-Yun
    Jeng, Yung-Ming
    Wang, Ju-Ming
    Chen, Phang-Iang
    Chang, Yi-Cheng
    Lee, Kuo-Fen
    Tsai, Ming-Daw
    Shew, Jin-Yuh
    Lee, Wen-Hwa
    MOLECULAR CELL, 2012, 48 (05) : 747 - 759
  • [50] Endoplasmic reticulum stress-inducible protein GRP94 is associated with an Mg2+-dependent serine kinase activity modulated by Ca2+ and GRP78/BiP
    Ramakrishnan, M
    Schonthal, AH
    Lee, AS
    JOURNAL OF CELLULAR PHYSIOLOGY, 1997, 170 (02) : 115 - 129