Antioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L. species

被引：196
作者：
Aktumsek, Abdurrahman [1 ]
Zengin, Gokhan [1 ]
Guler, Gokalp Ozmen [2 ]
Cakmak, Yavuz Selim [3 ]
Duran, Ahmet [1 ]
机构：
[1] Selcuk Univ, Fac Sci, Dept Biol, Konya, Turkey
[2] Necmettin Erbakan Univ, Ahmet Kelesoglu Educ Fac, Dept Biol Educ, Konya, Turkey
[3] Aksaray Univ, Fac Sci & Arts, Dept Biotechnol & Mol Biol, Aksaray, Turkey
来源：
FOOD AND CHEMICAL TOXICOLOGY | 2013年 / 55卷
关键词：
Centaurea; Antioxidant; Phenolics; Anticholinesterase activity; DIFFERENT SOLVENT EXTRACTS; CHOLINESTERASE-INHIBITORS; WEST ANATOLIA; ESSENTIAL OIL; CAPACITY; PEROXIDATION; POLYPHENOLS; WAGENITZ; TURKEY; FRUITS;
D O I：
10.1016/j.fct.2013.01.018
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
The methanol and aqueous extracts of three endemic Centaurea species (C. polypodiifolia var. pseudobehen, C pyrrhoblephara and C antalyense) were investigated for their antioxidant and cholinesterase inhibitory activities. The antioxidant activities of these extracts were evaluated by in vitro models including, phosphomolybdenum assay, free radical scavenging assays (DPPH and ABTS), beta-carotene/linoleic acid test system, metal chelating assay, FRAP assay, ferric and cupric reducing power. Cholinesterase inhibitory activities were examined using Ellman's calorimetric method. Total phenol, flavonoid, and saponin contents were also measured. Among the six Centaurea extracts evaluated, the highest antioxidant abilities were obtained from C polypodiifolia var. pseudobehen. Methanolic extracts from C polypodiifolia var. pseudobehen and C antalyense had a noticeable inhibition towards AChE and BChE. These findings suggest that Centaurea species could be an anticholinesterase agent and antioxidant resource in some industries, such as food, pharmacology, and cosmetics. (C) 2013 Elsevier Ltd. All rights reserved.
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页码：290 / 296
页数：7
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