Recent Advances in Total Synthesis of Alkaloids from α,β-Unsaturated Aldehydes

被引:12
作者
Vchislo, Nadezhda V. [1 ]
Verochkina, Ekaterina A. [1 ]
机构
[1] Russian Acad Sci, AE Favorsky Irkutsk Inst Chem, Siberian Branch, Favorsky Str 1, Irkutsk 664033, Russia
来源
CHEMISTRYSELECT | 2020年 / 5卷 / 31期
基金
俄罗斯基础研究基金会;
关键词
alpha; beta-unsaturated aldehydes; alkaloids; natural products; total synthesis; heterocycles; ENANTIOSELECTIVE TOTAL-SYNTHESIS; LYCOPODIUM ALKALOIDS; INDOLE ALKALOIDS; NATURAL-PRODUCTS; ORGANOCATALYTIC CASCADE; PHLEGMARINE ALKALOIDS; ANTIMALARIAL ACTIVITY; MANZAMINE ALKALOIDS; MICHAEL REACTION; ERGOT ALKALOIDS;
D O I
10.1002/slct.202002872
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Alkaloids are structurally complex pharmacologically valuable natural products, the synthesis of which attracts the attention of the world scientific community. This review summarizes and highlights the recent advancements in the total synthesis of different family alkaloids (such as Lycopodium, Manzamine, Indole, Amaryllidaceae, as well as other alkaloids) from transformations of alpha,beta-unsaturated aldehydes.
引用
收藏
页码:9579 / 9589
页数:11
相关论文
共 145 条
  • [101] Peng J., 2008, MODERN ALKALOIDS STR, V8, P189
  • [102] SYNTHESIS OF THE ANTI-TUMOR DIMERIC INDOLE ALKALOIDS FROM CATHARANTHUS SPECIES (VINBLASTINE GROUP)
    POTIER, P
    [J]. JOURNAL OF NATURAL PRODUCTS, 1980, 43 (01): : 72 - 86
  • [103] Natural and Synthetic Chromenes, Fused Chromenes, and Versatility of Dihydrobenzo[h]chromenes in Organic Synthesis
    Pratap, Ramendra
    Ram, Vishnu Ji
    [J]. CHEMICAL REVIEWS, 2014, 114 (20) : 10476 - 10526
  • [104] Manzamines A potential for novel cures
    Radwan, Mona
    Hanora, Amro
    Khalifa, Sherief
    Abou-El-Ela, Soad H.
    [J]. CELL CYCLE, 2012, 11 (09) : 1765 - 1772
  • [105] Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases
    Rao, Karumanchi V.
    Donia, Marwa S.
    Peng, Jiangnan
    Garcia-Palomero, Esther
    Alonso, Diana
    Martinez, Ana
    Medina, Miguel
    Franzblau, Scott G.
    Tekwani, Babu L.
    Khan, Shabana I.
    Wahyuono, Subagus
    Willett, Kristine L.
    Hamann, Mark T.
    [J]. JOURNAL OF NATURAL PRODUCTS, 2006, 69 (07): : 1034 - 1040
  • [106] Strategic approaches to the synthesis of pyrrolizidine and indolizidine alkaloids
    Ratmanova, Nina K.
    Andreev, Ivan A.
    Leontiev, Alexandre, V
    Momotova, Daria
    Novoselov, Anton M.
    Ivanova, Olga A.
    Trushkov, Igor, V
    [J]. TETRAHEDRON, 2020, 76 (14)
  • [107] Prevalence of Diarylprolinol Silyl Ethers as Catalysts in Total Synthesis and Patents
    Reyes-Rodriguez, Gabriel J.
    Rezayee, Nomaan M.
    Vidal-Albalat, Andreu
    Jorgensen, Karl Anker
    [J]. CHEMICAL REVIEWS, 2019, 119 (06) : 4221 - 4260
  • [108] Organocatalytic asymmetric 5-hydroxypyrrolidine synthesis:: a highly enantioselective route to 3-substituted proline derivatives
    Rios, Ramon
    Ibrahem, Ismail
    Vesely, Jan
    Sunden, Henrik
    Cordova, Armando
    [J]. TETRAHEDRON LETTERS, 2007, 48 (49) : 8695 - 8699
  • [109] Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis
    Robertson, Jeremy
    Stevens, Kiri
    [J]. NATURAL PRODUCT REPORTS, 2017, 34 (01) : 62 - 89
  • [110] Progress towards the Total Syntheses of Lycopodium Alkaloid, Lycopladine A
    Rodrigues, Lima
    Majik, Mahesh Satu
    [J]. ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2019, 8 (08) : 1151 - 1163