Role of Melanocortin 4 Receptor (Mc4R) in Obesity

被引:0
|
作者
Nwana, Naderge [1 ]
Dhir, Ravindra [2 ]
Yin, Xaoyan [2 ]
Ahima, Rexford [2 ]
机构
[1] Univ Maryland Eastern Shore, Princess Anne, MD USA
[2] Univ Penn, Philadelphia, PA 19104 USA
来源
FASEB JOURNAL | 2012年 / 26卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Melanocortin-4 receptor (MC4R) agonists for the treatment of obesity
    Nargund, Ravi P.
    Strack, Alison M.
    Fong, Tung M.
    JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (14) : 4035 - 4043
  • [2] Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency
    Collet, Tinh-Hai
    Dubern, Beatrice
    Mokrosinski, Jacek
    Connors, Hillori
    Keogh, Julia M.
    de Oliveira, Edson Mendes
    Henning, Elana
    Poitou-Bernert, Christine
    Oppert, Jean-Michel
    Tounian, Patrick
    Marchelli, Florence
    Alili, Rohia
    Le Beyec, Johanne
    Pepin, Dominique
    Lacorte, Jean-Marc
    Gottesdiener, Andrew
    Bounds, Rebecca
    Sharma, Shubh
    Folster, Cathy
    Henderson, Bart
    O'Rahilly, Stephen
    Stoner, Elizabeth
    Gottesdiener, Keith
    Panaro, Brandon L.
    Cone, Roger D.
    Clement, Karine
    Farooqi, I. Sadaf
    Van der Ploeg, Lex H. T.
    MOLECULAR METABOLISM, 2017, 6 (10): : 1321 - 1329
  • [3] A novel melanocortin 4 receptor (MC4R) gene mutation associated with morbid obesity
    Mergen, M
    Mergen, H
    Ozata, M
    Oner, R
    Oner, C
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (07): : 3448 - 3451
  • [4] New Melanocortin 4 Receptor (MC4R) Gene Mutations Associated With Adolescent Obesity
    Yang, Yingkui
    Chen, Min
    Haynes, Beverly
    Bray, Molly S.
    Harmon, Carroll M.
    OBESITY, 2011, 19 : S105 - S105
  • [5] Regulation of Melanocortin Receptor 4 (MC4R) Ciliary Trafficking
    Nachury, Maxence
    DIABETES, 2023, 72
  • [6] Melanocortin Pathways: Suppressed and Stimulated Melanocortin-4 Receptor (MC4R)
    Hainer, Vojtech
    Aldhoon Hainerova, Irena
    Kunesova, Marie
    Taxova Braunerova, Radka
    Zamrazilova, Hana
    Bendlova, Bela
    PHYSIOLOGICAL RESEARCH, 2020, 69 : S245 - S254
  • [7] Obesity due to melanocortin 4 receptor (MC4R) deficiency is associated with delayed gastric emptying
    Seelig, Eleonora
    Henning, Elana
    Keogh, Julia M.
    Gillett, Daniel
    Shin, Evelyn
    Buscombe, John
    van der Klaauw, Agatha A.
    Farooqi, I. Sadaf
    CLINICAL ENDOCRINOLOGY, 2022, 96 (02) : 270 - 275
  • [8] Melanocortin Receptor 4 (MC4R) Signaling System in Nile Tilapia
    Liu, Tianqiang
    Deng, Yue
    Zhang, Zheng
    Cao, Baolong
    Li, Jing
    Sun, Caiyun
    Hu, Zhixing
    Zhang, Jiannan
    Li, Juan
    Wang, Yajun
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (19) : 1 - 19
  • [9] Early onset obesity due to Melanocortin 4 receptor (MC4R) defect; Successful treatment with Semaglutide
    Gokul, Pon Ramya
    Apperley, Louise
    Parkinson, Jennifer
    Seniappan, Senthil
    HORMONE RESEARCH IN PAEDIATRICS, 2023, 96 : 231 - 231
  • [10] Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment
    Ayers, Kristin L.
    Glicksberg, Benjamin S.
    Garfield, Alastair S.
    Longerich, Simonne
    White, Joseph A.
    Yang, Pengwei
    Du, Lei
    Chittenden, Thomas W.
    Gulcher, Jeffery R.
    Roy, Sophie
    Fiedorek, Fred
    Gottesdiener, Keith
    Cohen, Sarah
    North, Kari E.
    Schadt, Eric E.
    Li, Shuyu D.
    Chen, Rong
    Van der Ploeg, Lex H. T.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2018, 103 (07): : 2601 - 2612