A Case with Non-Small Cell Cancer in the Left Lung Diagnosed Following Observation of Bilateral Diffuse Lung Uptake of Tc-99m-MDP on Bone Scintigraphy

Extraskeletal accumulation of Technetium-99m methylene diphosphonate (Tc-99m-MDP) can be seen in bone scintigraphy both in benign and malignant lesions. In malignant lesions, this phenomenon is usually associated with microscopic calcifications due to the abnormal calcium metabolism, and occurs most frequently in the lungs. In this case report, we present a patient with a non-small lung cancer diagnosed following observation of incidental bilateral lung MDP accumulation in bone scintigraphy. Therefore, the tracer distribution in the soft tissues needs to be carefully examined on bone scans and any unexpected visible soft tissue activity should be stated on the scintigraphy report.