Synthesis, characterization, and in vitro cytotoxicity of chitosan hydrogels containing nanogold

被引：2

作者：

Tyliszczak, Bozena ^{[1
]}

Kudlacik-Kramarczyk, Sonia ^{[2
]}

Drabczyk, Anna ^{[2
]}

Sobczak-Kupiec, Agnieszka ^{[3
]}

机构：

[1] Cracow Univ Technol, Dept Chem & Technol Polymers, Warszawska 24, PL-31155 Krakow, Poland

[2] Cracow Univ Technol, Fac Chem Engn & Technol, Warszawska 24, PL-31155 Krakow, Poland

[3] Cracow Univ Technol, Inst Inorgan Chem & Technol, Krakow, Poland

来源：

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS | 2019年 / 68卷 / 04期

关键词：

Chitosan; cytotoxicity; dermal cells; gold nanoparticles; hydrogels; photopolymerization; CONDUCTIVE INJECTABLE HYDROGELS; GOLD NANOPARTICLES; CONTROLLED-RELEASE; ANTIBACTERIAL; SCAFFOLD; DESIGN; CHITIN; PH;

D O I：

10.1080/00914037.2018.1429438

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Hydrogels due to their unique properties are characterized by a wide range of applications. In presented research a series of hydrogel based on chitosan and modified with nanogold have been prepared by photopolymerization. Based on the research it can be concluded that presented hydrogels are interesting materials that can play a key role in medicine. They are characterized by biocompatibility to simulated physiological fluids and do not show any cytotoxicity to the dermal cells. Furthermore, they are characterized by relatively high sorption capacity. These results show the possibility of the potential use of these hydrogels for biomedical purposes. [GRAPHICS]

引用

页码：175 / 182

页数：8

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