Treatment of Zollinger-Ellison Syndrome

被引：16
|
作者：
Tomassetti, Paola [1 ]
Campana, Davide [1 ]
Piscitelli, Lydia [1 ]
Mazzotta, Elena [1 ]
Brocchi, Emilio [1 ]
Pezzilli, Raffaele [1 ]
Corinaldesi, Roberto [1 ]
机构：
[1] Univ Bologna, Policlin S Orsola Malpighi, Dept Internal Med & Gastroenterol, I-40138 Bologna, Italy
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2005年 / 11卷 / 35期
关键词：
Gastrinoma; Zollinger-Ellison Syndrome; MEN; 1; Proton pump inhibitors; Somatostatin analogs; Chemoembolization;
D O I：
10.3748/wjg.v11.i35.5423
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
In this article, we have reviewed the main therapeutic measures for the treatment of Zollinger-Ellison syndrome (ZES). Review of the literature was based on computer searches (Pub-Med, Index Medicus) and personal experiences. We have evaluated all the measures now available for treating patients with sporadic gastrinomas or gastrinomas associated with Multiple Endocrine Neoplasia Type 1, (MEN 1) including medical therapy such as antisecretory drugs and somatostatin analogs (SST), chemotherapy and chemoembolization, and surgical procedures. In ZES patients, the best therapeutic procedure is surgery which, if radical, can be curative. Medical treatment can be the best palliative therapy and should be used, when possible, in association with surgery, in a multimodal therapeutic approach. (C) 2005 The WJG Press and Elsevier Inc. All rights reserved.
引用
收藏
页码：5423 / 5432
页数：10
相关论文
共 50 条
  • [21] Diagnosis of Zollinger-Ellison syndrome:Increasingly difficult
    Tetsuhide Ito
    Guillaume Cadiot
    Robert T Jensen
    World Journal of Gastroenterology, 2012, 18 (39) : 5495 - 5503
  • [22] The Zollinger-Ellison Syndrome and Mismeasurement of Gastrin
    Rehfeld, Jens F.
    Gingras, Marie-Helene
    Bardram, Linda
    Hilsted, Linda
    Goetze, Jens P.
    Poitras, Pierre
    GASTROENTEROLOGY, 2011, 140 (05) : 1444 - 1453
  • [23] MANAGEMENT OF PATIENTS WITH ZOLLINGER-ELLISON SYNDROME
    MEKO, JB
    NORTON, JA
    ANNUAL REVIEW OF MEDICINE, 1995, 46 : 395 - 411
  • [24] The Zollinger-Ellison syndrome: is there a role for somatostatin analogues in the treatment of the gastrinoma?
    Valentina Guarnotta
    Chiara Martini
    Maria Vittoria Davì
    Genoveffa Pizza
    Annamaria Colao
    Antongiulio Faggiano
    Endocrine, 2018, 60 : 15 - 27
  • [25] The glucagon provocative test for the diagnosis and treatment of Zollinger-Ellison syndrome
    Shibata, Chikashi
    Funayama, Yuji
    Fukushima, Kouhei
    Ueno, Tatsuya
    Kohyama, Atsushi
    Satoh, Kennichi
    Shimosegawa, Tooru
    Yamagiwa, Tetsuya
    Sasaki, Iwao
    JOURNAL OF GASTROINTESTINAL SURGERY, 2008, 12 (02) : 344 - 349
  • [26] Prospective Evaluation of Results of Reoperation in Zollinger-Ellison Syndrome
    Norton, Jeffrey A.
    Krampitz, Geoffrey W.
    Poultsides, George A.
    Visser, Brendan C.
    Fraker, Douglas L.
    Alexander, H. Richard
    Jensen, Robert T.
    ANNALS OF SURGERY, 2018, 267 (04) : 782 - 788
  • [27] The Zollinger-Ellison Syndrome: Dangers and Consequences of Interrupting Antisecretory Treatment
    Poitras, Pierre
    Gingras, Marie-Helene
    Rehfeld, Jens F.
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2012, 10 (02) : 199 - 202
  • [28] Zollinger-Ellison syndrome: Presentation, response to therapy, and outcome
    Wilcox, C. Mel
    Seay, Toni
    Arcury, Justin T.
    Mohnen, Jean
    Hirschowitz, Basil I.
    DIGESTIVE AND LIVER DISEASE, 2011, 43 (06) : 439 - 443
  • [29] Delayed Management of Zollinger-Ellison Syndrome in a Noncompliant Patient
    Klimko, Artsiom
    Plotogea, Oana
    Constantinescu, Alexandru
    Constantinescu, Gabriel
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2020, 12 (06)
  • [30] Zollinger-Ellison Syndrome: A Rare Case of Chronic Diarrhea
    Aamar, Ali
    Madhani, Kamraan
    Virk, Hafeezulhassan
    Butt, Zeeshan
    GASTROENTEROLOGY RESEARCH, 2016, 9 (06) : 103 - 104
12345