A Unifying Nitrososynthase Involved in Nitrosugar Biosynthesis

被引：26
作者：
Hu, Yunfeng
Al-Mestarihi, Ahmad
Grimes, Catherine L.
Kahne, Daniel
Bachmann, Brian O. [1 ]
机构：
[1] Vanderbilt Univ, Dept Chem, Nashville, TN 37235 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 47期
关键词：
D O I：
10.1021/ja8051415
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein we describe the cloning, functional expression and initial characterization of ORF36 from Micromonospora carbonacae var. africana and rubN8 from Streptomyces achromogenes var. rubradiris. The purified enzymes play the same role, the double-oxidation of TDP-evernosamine to TDP-evernitrosose in the everninomycin and rubradirin pathways, respectively.
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页码：15756 / +
页数：3
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